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Pregnancy and Childbirth

Early vaginal progesterone versus Placebo in Twin Pregnancies for prevention of spontaneous preterm birth (EVENTS): A randomised double-blind trial

Am J Obstet Gynecol.

Rehal A, Benkő Z, De Paco Matallana C, Syngelaki A, Janga D, Cicero S, Akolekar R, Singh M, Chaveeva P, Burgos J, Molina FS, Savvidou M, De La Calle M, Persico N, Quezada Rojas MS, Sau A, Greco E, O'Gorman N, Plasencia W, Pereira S, Jani JC, Valino N, Gil MDM, Maclagan K, Wright A, Wright D, Nicolaides KH

doi: 10.1016/j.ajog.2020.06.050.

Pregnancy and Childbirth

Valaciclovir to prevent vertical transmission of cytomegalovirus after maternal primary infection during pregnancy: a randomised, double-blind, placebo-controlled trial

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Shahar-Nissan K, Pardo J, Peled O, Krause I, Bilavsky E, Wiznitzer A, Hadar E, Amir J

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Pregnancy and Childbirth

Aspirin versus Placebo in Pregnancies at High Risk for Preterm Preeclampsia

N Engl J Med.

Rolnik DL, Wright D, Poon LC, O'Gorman N, Syngelaki A, de Paco Matallana C, Akolekar R, Cicero S, Janga D, Singh M, Molina FS, Persico N, Jani JC, Plasencia W, Papaioannou G, Tenenbaum-Gavish K, Meiri H, Gizurarson S, Maclagan K, Nicolaides KH

doi: 10.1056/NEJMoa1704559.

Pregnancy and Childbirth

Ursodeoxycholic acid versus placebo in women with intrahepatic cholestasis of pregnancy (PITCHES): a randomised controlled trial

Lancet.

Chappell LC, Bell JL, Smith A, Linsell L, Juszczak E, Dixon PH, Chambers J, Hunter R, Dorling J, Williamson C, Thornton JG, PITCHES study group.

doi: 10.1016/S0140-6736(19)31270-X.

Pregnancy and Childbirth

Cervical pessary for preventing preterm birth in twin pregnancies with maternal short cervix after an episode of threatened preterm labour: randomised controlled trial

Am J Obstet Gynecol.

Merced C, Goya , Pratcorona L, Rodó C, Llurba E, Higueras T, Cabero L, Carreras E, Trial Group

doi: 10.1016/j.ajog.2019.02.035.

Pregnancy and Childbirth

Mifepristone and misoprostol versus misoprostol alone for the management of missed miscarriage (MifeMiso): a randomised, double-blind, placebo-controlled trial

Lancet.

Chu JJ, Devall AJ, Beeson LE, Hardy P, Cheed V, Sun Y, Roberts TE, Ogwulu CO, Williams E, Jones LL, La Fontaine Papadopoulos JH, Bender-Atik R, Brewin J, Hinshaw K, Choudhary M, Ahmed A, Naftalin J, Nunes N, Oliver A, Izzat F, Bhatia K, Hassan I, Jeve Y, Hamilton J, Deb S, Bottomley C, Ross J, Watkins L, Underwood M, Cheong Y, Kumar CS, Gupta P, Small R, Pringle S, Hodge F, Shahid A, Gallos ID, Horne AW, Quenby S, Coomarasamy A

doi: 10.1016/S0140-6736(20)31788-8.

Pregnancy and Childbirth

Prospective Randomized Double-Blind, Placebo Controlled Evaluation of the Pharmacokinetics, Safety and Efficacy of Recombinant Antithrombin Versus Placebo in Preterm Preeclampsia (PRESERVE-1)

Am J Obstet Gynecol.

Paidas MJ, Tita ATN, Macones GA, Saade GA, Ehrenkranz RA, Triche EW, Streisand JB, Lam GK, Magann EF, Lewis DF, Dombrowski MP, Werner EF, Branch DW, Habli MA, Grotegut CA, Silver RM, Longo SA, Amon E, Cleary KL, How HY, Novotny SR, Grobman WA, Whiteman VE, Wing DA, Scifres CM, Sibai BM

doi: 10.1016/j.ajog.2020.08.004.

Overactive Bladder

Efficacy of Daily Low-dose Tadalafil for Treating Overactive Bladder: Results of a Randomized, Double-blind, Placebo-controlled Trial

Urology.

Chen H, Wang F, Yu Z, Zhang Y, Liu C, Dai S, Chen B, Lv J

doi: 10.1016/j.urology.2016.11.008.

Pregnancy and Childbirth

Maternal intramuscular dexamethasone versus betamethasone before preterm birth (ASTEROID): a multicentre, double-blind, randomised controlled trial

Lancet Child Adolesc Health.

Crowther CA, Ashwood P, Andersen CC, Middleton PF, Tran T, Doyle LW, Robinson JS, Harding JE, ASTEROID Study Group.

doi: 10.1016/S2352-4642(19)30292-5.

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