Usefulness of a Double-Blind Placebo-Controlled Response Test to Demonstrate Rapid Onset Analgesia with Phenytoin 10% Cream in Polyneuropathy

Anesthesia and HyperthermiaEpidural AnesthesiaGeneral AnesthesiaMechanical VentilationLabor and DeliveryObesity and AnesthesiaPediatric AnesthesiaPerioperative ManagementRegional AnesthesiaSeniors and AnesthesiaSpinal Anesthesia

Determination of equi-analgesic doses of inhaled methoxyflurane versus intravenous fentanyl using the cold pressor test in volunteers: a randomised, double-blinded, placebo-controlled crossover study

Br J Anaesth

Lenz H, Høiseth LØ, Comelon M, Draegni T, Rosseland LA

doi: 10.1016/j.bja.2020.12.045

Pain ReliefPostoperative Pain

Preemptive analgesia for postoperative pain relief in thoracolumbosacral spine operations: a double-blind, placebo-controlled randomized trial

J Neurosurg Spine.

Aglio LS, Abd-El-Barr MM, Orhurhu V, Kim GY, Zhou J, Gugino LD, Crossley LJ, Gosnell JL, Chi JH, Groff MW

doi: 10.3171/

Chronic Pain

Individuals with chronic pain have the same response to placebo analgesia as healthy controls in terms of magnitude and reproducibility

Pain.

Power A, Brown CA, Sivan M, Lenton A, Rainey T, El-Deredy W, Peter Jones AK, Watson A

doi: 10.1097/j.pain.0000000000001966.

General Anesthesia

Thoracic Epidural Analgesia With Levobupivacaine Reduces Remifentanil and Propofol Consumption Evaluated by Closed-Loop Titration Guided by the Bispectral Index: A Double-blind Placebo-controlled Study

Anesth Analg.

Dumans-Nizard V, Le Guen M, Sage E, Chazot T, Fischler M, Liu N

doi: 10.1213/

Can early oral prolonged-release oxycodone with or without naloxone reduce the duration of epidural analgesia after cystectomy? A 3-arm, randomized, double-blind, placebo-controlled trial

Pain.

Schneider MP, Löffel LM, Furrer MA, Burkhard FC, Kleeb B, Curatolo M, Wuethrich PY

doi: 10.1097/

COMMENTED

Chronic Pain

The Pharmacokinetics, Efficacy, and Safety of a Novel Selective-Dose Cannabis Inhaler in Patients with Chronic Pain: A Randomized, Double-Blinded, Placebo-Controlled Trial

★ 3 Recommended and commented by Dr Roland Schreiber, Faculty Member

Eur J Pain.

Almog S, Aharon-Peretz J, Vulfsons S, Ogintz M, Abalia H, Lupo T, Hayon Y, Eisenberg E

doi: 10.1002/ejp.1605.

Pain Management

Efficacy and safety of a monthly buprenorphine depot injection for opioid use disorder: a multicentre, randomised, double-blind, placebo-controlled, phase 3 trial

Lancet.

Haight BR, Learned SM, Laffont CM, Fudala PJ, Zhao Y, Garofalo AS, Greenwald MK, Nadipelli VR, Ling W, Heidbreder C; RB-US-13-0001 Study Investigators.

doi: 10.1016/S0140-6736(18)32259-1.

Back Pain

Treatment of recent onset low back pain with periradicular injections of meloxicam: a randomized, double blind, placebo controlled cross-over study

Minerva Anestesiol.

Borghi B, Aurini L, White PF, Tognù A, Rossi B, Fini G, Rucci P, Greggi T, Borghi R

doi: 10.23736/

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Acute Pain

Tramadol/dexketoprofen (TRAM/DKP) compared with tramadol/paracetamol in moderate to severe acute pain: results of a randomised, double-blind, placebo and active-controlled, parallel group trial in the impacted third molar extraction pain model (DAVID study)

BMJ Open.

Gay-Escoda C, Hanna M, Montero A, Dietrich T, Milleri S, Giergiel E, Zoltán TB, Varassi G

doi: 10.1136/bmjopen-

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