Serum B cell maturation antigen (BCMA) levels differentiate primary antibody deficiencies

Immunotherapy

Chimeric Antigen Receptor-Modified T Cell Therapy in Multiple Myeloma: Beyond B Cell Maturation Antigen

Front Immunol.

Timmers M, Roex G, Wang Y, Campillo-Davo D, Van Tendeloo VFI, Chu Y, Berneman ZN, Luo F, Van Acker HH, Anguille S

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Immunodeficiency

Predominantly Antibody-Deficient Patients With Non-infectious Complications Have Reduced Naive B, Treg, Th17, and Tfh17 Cells

Front Immunol.

Edwards ESJ, Bosco JJ, Aui PM, Stirling RG, Cameron PU, Chatelier J, Hore-Lacy F, O'Hehir RE, van Zelm MC

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Arthritis Rheumatol.

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Rheumatoid Arthritis

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Scherer HU, Huizinga TWJ, Krönke G, Schett G, Toes REM

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Activated peripheral blood B cells in rheumatoid arthritis and relationship to anti-TNF treatment and response: randomized clinical trial for anti-TNF effects on B cells

Arthritis Rheumatol

Meednu N, Barnard J, Callahan K, Coca A, Marston B, Thiele R, Tabechian D, Bolster M, Curtis J, Mackay M, Graf J, Keating R, Smith E, Boyle K, Keyes-Elstein L, Welch B, Goldmuntz E, Anolik JH

doi: 10.1002/art.41941

Immunodeficiency

The clinical and immunological features of patients with primary antibody deficiencies

Endocr Metab Immune Disord Drug Targets.

Azizi G, Bagheri Y, Tavakol M, Askarimoghaddam F, Poorrostami K, Rafiemanesh H, Yazdani R, Kiaee F, Habibi S, Abouhamzeh K, Mohammadi H, Qorbani M, Abolhassani H, Aghamohammadi A

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Genome-edited, donor-derived allogeneic anti-CD19 chimeric antigen receptor T cells in paediatric and adult B-cell acute lymphoblastic leukaemia: results of two phase 1 studies

Lancet

Benjamin R, Graham C, Yallop D, Jozwik A, Mirci-Danicar OC, Lucchini G, Pinner D, Jain N, Kantarjian H, Boissel N, Maus MV, Frigault MJ, Baruchel A, Mohty M, Gianella-Borradori A, Binlich F, Balandraud S, Vitry F, Thomas E, Philippe A, Fouliard S, Dupouy S, Marchiq I, Almena-Carrasco M, Ferry N, Arnould S, Konto C, Veys P, Qasim W, UCART19 Group.

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Immunodeficiency

Immunological and Clinical Phenotyping in Primary Antibody Deficiencies: a Growing Disease Spectrum

J Clin Immunol.

Shin JJ, Liauw D, Siddiqui S, Lee J, Chung EJ, Steele R, Hsu FI, Price C, Kang I

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Immunodeficiency

Defective TLR9-driven STAT3 activation in B cells of patients with CVID

Clin Immunol.

Borzutzky A, Rauter I, Fried A, Rachid R, McDonald DR, Hammarstrom L, Grimbacher B, Abraham RS, Geha RS

doi: 10.1016/j.clim.2018.08.008.

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Chimeric Antigen Receptor-Modified T Cell Therapy in Multiple Myeloma: Beyond B Cell Maturation Antigen

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Abatacept attenuates T follicular helper-cell-dependent B-cell hyperactivity in primary Sjögren's syndrome

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