Rare genetic variants in interleukin-37 link this anti-inflammatory cytokine to the pathogenesis and treatment of gout

Osteoarthritis

Effectiveness of non-steroidal anti-inflammatory drugs for the treatment of pain in knee and hip osteoarthritis: a network meta-analysis

Lancet

da Costa BR, Reichenbach S, Keller N, Nartey L, Wandel S, Jüni P, Trelle S

doi: 10.1016/

COMMENTED

Spinal Disorders

Ixekizumab, an interleukin-17A antagonist in the treatment of ankylosing spondylitis or radiographic axial spondyloarthritis in patients previously untreated with biological disease-modifying anti-rheumatic drugs (COAST-V): 16 week results of a phase 3 randomised, double-blind, active-controlled and placebo-controlled trial

Lancet.

van der Heijde D, Cheng-Chung Wei J, Dougados M, Mease P, Deodhar A, Maksymowych WP, Van den Bosch F, Sieper J, Tomita T, Landewé R, Zhao F, Krishnan E, Adams DH, Pangallo B, Carlier H; COAST-V study group

doi: 10.1016/S0140-

RECOMMENDED

Further Publications Immunology

Efficacy of early anti-inflammatory treatment with high doses IV Anakinra with or without glucocorticoids in patients with severe COVID-19 pneumonia

★ 2 Recommended by Dr Martin Frey, Faculty Member

J Allergy Clin Immunol

Pontali E, Volpi S, Signori A, Antonucci G, Castellaneta M, Buzzi D, Montale A, Bustaffa M, Angelelli A, Caorsi R, Giambruno E, Bobbio N, Feasi M, Gueli I, Tricerri F, Calautti F, Castagnola E, Moscatelli A, Rollandi GA, Ravelli A, Cassola G, Sormani MP, Gattorno M

doi: 10.1016/j.jaci.2021.01.024

Further Publications Rheumatology

Arterial wall inflammation in rheumatoid arthritis is reduced by anti-inflammatory treatment

Semin Arthritis Rheum

Blanken AB, Agca R, van Sijl AM, Voskuyl AE, Boellaard R, Smulders YM, van der Laken CJ, Nurmohamed MT

doi: 10.1016/j.semarthrit.2021.03.008

Interleukin-10: Role in increasing susceptibility and pathogenesis of rheumatic fever/rheumatic heart disease.

Cytokine.

Sharma N, Toor D

doi: 10.1016/j.cyto.2016.11.010.

Psoriatic ArthritisRheumatoid ArthritisSpinal Disorders

Associations between certolizumab pegol serum levels, anti-drug antibodies and treatment response in patients with inflammatory joint diseases: data from the NOR-DMARD study

Arthritis Res Ther.

Gehin JE, Goll GL, Warren DJ, Syversen SW, Sexton J, Strand EK, Kvien TK, Bolstad N, Lie E

doi: 10.1186/s13075-019-2009-5.

COMMENTED

PsoriasisRheumatoid Arthritis

Anti-tumour necrosis factor-α therapy and recurrent or new primary cancers in patients with inflammatory bowel disease, rheumatoid arthritis, or psoriasis and previous cancer in Denmark: a nationwide, population-based cohort study

★ 3 Recommended and commented by Dr Heino Prillwitz, Faculty Member

★ 3 Recommended and commented by PD Dr Luc Biedermann, Faculty Member

doi: 10.1016/S2468-1253(19)30362-0.

Rheumatoid Arthritis

Investigation of genetically regulated gene expression and response to treatment in rheumatoid arthritis highlights an association between IL18RAP expression and treatment response

Ann Rheum Dis.

Cherlin S, Lewis MJ, Plant D, Nair N, Goldmann K, Tzanis E, Barnes MR, McKeigue P, Barrett JH, Pitzalis C, Barton A, MATURA Consortium., Cordell HJ

doi: 10.1136/annrheumdis-2020-217204.

Further Publications Immunology

The Severity of Herpes Zoster in Inflammatory Bowel Disease Patients Treated With Anti-TNF Agents

Inflamm Bowel Dis.

Khan N, Trivedi C, Shah Y, Patel D, Lewis J, Yang YX

doi: 10.1093/ibd/izx115.

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