Loss of balance between protective and pro-inflammatory synovial tissue T-cell polyfunctionality predates clinical onset of rheumatoid arthritis

T Cells

Counter-regulation of regulatory T cells by autoreactive CD8+ T cells in rheumatoid arthritis

doi: 10.1016/j.jaut.2019.02.001.

Rheumatoid Arthritis

Synovial tissue signatures enhance clinical classification and prognostic/treatment response algorithms in early inflammatory arthritis and predict requirement for subsequent biological therapy: results from the pathobiology of early arthritis cohort (PEAC)

Ann Rheum Dis.

Lliso-Ribera G, Humby F, Lewis M, Nerviani A, Mauro D, Rivellese F, Kelly S, Hands R, Bene F, Ramamoorthi N, Hackney JA, Cauli A, Choy EH, Filer A, Taylor PC, McInnes I, Townsend MJ, Pitzalis C

doi: 10.1136/annrheumdis-2019-215751.

T CellsRheumatoid Arthritis

Mesenchymal Stem Cells Improve Rheumatoid Arthritis Progression by Controlling Memory T Cell Response

Front Immunol.

Luque-Campos N, Contreras-López RA, Jose Paredes-Martínez M, Torres MJ, Bahraoui S, Wei M, Espinoza F, Djouad F, Elizondo-Vega RJ, Luz-Crawford P

doi: 10.3389/fimmu.

T CellsRheumatoid Arthritis

Dendritic cells, T cells and their interaction in rheumatoid arthritis

Clin Exp Immunol.

Wehr P, Purvis H, Law SC, Thomas R

doi: 10.1111/cei.13256.

Rheumatoid Arthritis

Differential effects of IL-6 blockade tocilizumab and TNF inhibitors on angiogenesis in synovial tissues from patients with rheumatoid arthritis.

Mod Rheumatol.

Hirohata S, Abe A, Murasawa A, Kanamono T, Tomita T, Yoshikawa H

T CellsRheumatoid Arthritis

Effect of rituximab treatment on T and B cell subsets in lymph node biopsies of patients with rheumatoid arthritis

Rheumatology (Oxford).

Ramwadhdoebe TH, van Baarsen LGM, Boumans MJH, Bruijnen STG, Safy M, Berger FH, Semmelink JF, van der Laken CJ, Gerlag DM, Thurlings RM, Tak PP

doi: 10.1093/rheumatology/key428.

Rheumatoid Arthritis

Disease associated anti-citrullinated protein memory B cells in rheumatoid arthritis persist in clinical remission.

Arthritis Rheumatol.

Pelzek AJ, Grönwall C, Rosenthal P, Greenberg JD, McGeachy M, Moreland L, Rigby WF, Silverman GJ

doi: 10.1002/art.40053.

Rheumatoid Arthritis

Visualising the interaction of CD4 T cells and DCs in the evolution of inflammatory arthritis

Ann Rheum Dis.

Prendergast CT, Patakas A, Al-Khabouri S, McIntyre CL, McInnes I, Brewer JM, Garside P, Benson RA

doi: 10.1136/annrheumdis-

Further Publications Rheumatology

Activated peripheral blood B cells in rheumatoid arthritis and relationship to anti-TNF treatment and response: randomized clinical trial for anti-TNF effects on B cells

Arthritis Rheumatol

Meednu N, Barnard J, Callahan K, Coca A, Marston B, Thiele R, Tabechian D, Bolster M, Curtis J, Mackay M, Graf J, Keating R, Smith E, Boyle K, Keyes-Elstein L, Welch B, Goldmuntz E, Anolik JH

doi: 10.1002/art.41941

Related content

Counter-regulation of regulatory T cells by autoreactive CD8+ T cells in rheumatoid arthritis

Synovial tissue signatures enhance clinical classification and prognostic/treatment response algorithms in early inflammatory arthritis and predict requirement for subsequent biological therapy: results from the pathobiology of early arthritis cohort (PEAC)

Mesenchymal Stem Cells Improve Rheumatoid Arthritis Progression by Controlling Memory T Cell Response

Dendritic cells, T cells and their interaction in rheumatoid arthritis

Differential effects of IL-6 blockade tocilizumab and TNF inhibitors on angiogenesis in synovial tissues from patients with rheumatoid arthritis.

Effect of rituximab treatment on T and B cell subsets in lymph node biopsies of patients with rheumatoid arthritis

Disease associated anti-citrullinated protein memory B cells in rheumatoid arthritis persist in clinical remission.

Visualising the interaction of CD4 T cells and DCs in the evolution of inflammatory arthritis

Activated peripheral blood B cells in rheumatoid arthritis and relationship to anti-TNF treatment and response: randomized clinical trial for anti-TNF effects on B cells