Increased expression of Fas on group 2 and 3 innate lymphoid cells is associated with an interferon signature in systemic lupus erythematosus and Sjögren's syndrome

Autoimmune DiseaseSystemic Lupus Erythematosus

Elevated Semaphorin5A in systemic lupus erythematosus is in association with disease activity and lupus nephritis.

Clin Exp Immunol.

Du Y, Wu X, Chen M, Wang W, Xv W, Ye L, Wu D, Xue J, Sun W, Luo J, Wu H

doi: 10.1111/cei.12924.

Allergic Diseases

Increased Group 2 Innate Lymphoid Cells Are Correlated with Eosinophilic Granulocytes in Patients with Allergic Airway Inflammation

Int Arch Allergy Immunol.

Yu QN, Tan WP, Fan XL, Guo YB, Qin ZL, Li CL, Chen D, Lin ZB, Wen W, Fu QL

doi: 10.1159/000488050.

Systemic Lupus Erythematosus

Two shared immune cell signatures stratify patients with Sjögren's syndrome and systemic lupus erythematosus with potential therapeutic implications

Arthritis Rheumatol

Martin-Gutierrez L, Peng J, Thompson NL, Robinson GA, Naja M, Peckham H, Wu W, J'bari H, Ahwireng N, Waddington KE, Bradford CM, Varnier G, Gandhi A, Radmore R, Gupta V, Isenberg DA, Jury EC, Ciurtin C

doi: 10.1002/art.41708

T CellsSystemic Lupus Erythematosus

Hypomethylation of STAT1 and HLA-DRB1 is associated with type-I interferon-dependent HLA-DRB1 expression in lupus CD8+ T cells

Ann Rheum Dis.

Miller S, Tsou PS, Coit P, Gensterblum-Miller E, Renauer P, Rohraff DM, Kilian NC, Schonfeld M, Sawalha AH

doi: 10.1136/annrheumdis-

Systemic Lupus Erythematosus

Paradoxical association between blood modular interferon signatures and quality of life in patients with systemic lupus erythematosus

Rheumatology (Oxford).

Seguier J, Jouve E, Bobot M, Whalen E, Dussol B, Gentile S, Burtey S, Halfon P, Retornaz F, Chaussabel D, Chiche L, Jourde-Chiche N

doi: 10.1093/rheumatology/kez541.

Systemic Lupus Erythematosus

Rivaroxaban versus warfarin to treat patients with thrombotic antiphospholipid syndrome, with or without systemic lupus erythematosus (RAPS): a randomised, controlled, open-label, phase 2/3, non-inferiority trial

Lancet Haematol.

Cohen H, Hunt BJ, Efthymiou M, Arachchillage DR, Mackie IJ, Clawson S, Sylvestre Y, Machin SJ, Bertolaccini ML, Ruiz-Castellano M, Muirhead N, Doré CJ, Khamashta M, Isenberg DA; RAPS trial investigators

doi: 10.1016/

Systemic Lupus Erythematosus

Sjögren's syndrome in Systemic Lupus Erythematosus - a subset characterized by a systemic inflammatory state

J Rheumatol.

Ruacho G, Kvarnström M, Zickert A, Oke V, Rönnelid J, Eketjäll S, Elvin K, Gunnarsson I, Svenungsson E

doi: 10.3899/jrheum.190250.

Systemic Lupus Erythematosus

Increased levels of anti-dsDNA antibodies in immune complexes before treatment with belimumab associate with clinical response in patients with systemic lupus erythematosus

Arthritis Res Ther.

Sohrabian A, Parodis I, Carlströmer-Berthén N, Frodlund M, Jönsen A, Zickert A, Sjöwall C, Bengtsson AA, Gunnarsson I, Rönnelid J

doi: 10.1186/s13075-019-2056-y.

Systemic Lupus Erythematosus

The role of baseline BLyS levels and type 1 interferon-inducible gene signature status in determining belimumab response in systemic lupus erythematosus: a post hoc meta-analysis

Arthritis Res Ther.

Wilkinson C, Henderson RB, Jones-Leone AR, Flint SM, Lennon M, Levy RA, Ji B, Bass DL, Roth D

doi: 10.1186/s13075-020-02177-0.

Related content

Elevated Semaphorin5A in systemic lupus erythematosus is in association with disease activity and lupus nephritis.

Increased Group 2 Innate Lymphoid Cells Are Correlated with Eosinophilic Granulocytes in Patients with Allergic Airway Inflammation

Two shared immune cell signatures stratify patients with Sjögren's syndrome and systemic lupus erythematosus with potential therapeutic implications

Hypomethylation of STAT1 and HLA-DRB1 is associated with type-I interferon-dependent HLA-DRB1 expression in lupus CD8+ T cells

Paradoxical association between blood modular interferon signatures and quality of life in patients with systemic lupus erythematosus

Rivaroxaban versus warfarin to treat patients with thrombotic antiphospholipid syndrome, with or without systemic lupus erythematosus (RAPS): a randomised, controlled, open-label, phase 2/3, non-inferiority trial

Sjögren's syndrome in Systemic Lupus Erythematosus - a subset characterized by a systemic inflammatory state

Increased levels of anti-dsDNA antibodies in immune complexes before treatment with belimumab associate with clinical response in patients with systemic lupus erythematosus

The role of baseline BLyS levels and type 1 interferon-inducible gene signature status in determining belimumab response in systemic lupus erythematosus: a post hoc meta-analysis