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Anakinra for the treatment of acute gout flares: a randomized, double-blind, placebo-controlled, active-comparator, non-inferiority trial
Gout
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Psoriatic Arthritis
Guselkumab in patients with active psoriatic arthritis who were biologic-naive or had previously received TNFα inhibitor treatment (DISCOVER-1): a double-blind, randomised, placebo-controlled phase 3 trial
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Dr Heino Prillwitz, Faculty Member
doi: 10.1016/S0140-6736(20)30265-8.
COMMENTED
Psoriasis
Risankizumab compared with adalimumab in patients with moderate-to-severe plaque psoriasis (IMMvent): a randomised, double-blind, active-comparator-controlled phase 3 trial
Lancet.
Reich K, Gooderham M, Thaçi D, Crowley JJ, Ryan C, Krueger JG, Tsai TF, Flack M, Gu Y, Williams DA, Thompson EHZ, Paul C
doi: 10.1016/S0140-6736(19)30952-3.
Osteoporosis
Denosumab versus risedronate in glucocorticoid-induced osteoporosis: a multicentre, randomised, double-blind, active-controlled, double-dummy, non-inferiority study
Lancet Diabetes Endocrinol.
Saag KG, Wagman RB, Geusens P, Adachi JD, Messina OD, Emkey R, Chapurlat R, Wang A, Pannacciulli N, Lems WF
doi: 10.1016/
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French maritime pine bark extract (pycnogenol) in association with triple combination cream for the treatment of facial melasma in women: a double-blind, randomized, placebo-controlled trial
J Eur Acad Dermatol Venereol.
Lima PB, Alexandria Ferreira Dias J, Esposito ACC, Miot LDB, Miot HA
doi: 10.1111/jdv.16896.
Psoriasis
Long-term efficacy and safety of brodalumab in the treatment of psoriasis: 120-week results from the randomized, double-blind, placebo- and active comparator-controlled phase 3 AMAGINE-2 trial
J Am Acad Dermatol.
Puig L, Lebwohl M, Bachelez H, Sobell J, Jacobson AA
doi: 10.1016/j.jaad.
Acne
A randomized, double-blind, placebo-controlled trial to determine the efficacy and safety of lactoferrin with vitamin E and zinc as an oral therapy for mild to moderate acne vulgaris
Int J Dermatol.
Chan H, Chan G, Santos J, Dee K, Co JK
doi: 10.1111/ijd.13607.
Further Publications DermatologyFurther Publications ImmunologyFurther Publications Rheumatology
Ceftobiprole Compared With Vancomycin Plus Aztreonam in the Treatment of Acute Bacterial Skin and Skin Structure Infections: Results of a Phase 3, Randomized, Double-blind Trial (TARGET)
Clin Infect Dis.
Overcash JS, Kim C, Keech R, Gumenchuk I, Ninov B, Gonzalez-Rojas Y, Waters M, Simeonov S, Engelhardt M, Saulay M, Ionescu D, Smart JI, Jones ME, Hamed KA
doi: 10.1093/cid/ciaa974.
Allergic Diseases
A 300°IR sublingual tablet is an effective, safe treatment for house-dust-mite-induced allergic rhinitis: an international, double-blind, placebo-controlled, randomized Phase III clinical trial
J Allergy Clin Immunol
Demoly P, Corren J, Creticos P, De Blay F, Gevaert P, Hellings P, Kowal K, Le Gall M, Nenasheva N, Passalacqua G, Pfaar O, Tortajada-Girbés M, Vidal C, Worm M, Casale TB
doi: 10.1016/j.jaci.2020.07.036
Allergic Diseases
A 300°IR sublingual tablet is an effective, safe treatment for house-dust-mite-induced allergic rhinitis: an international, double-blind, placebo-controlled, randomized Phase III clinical trial
J Allergy Clin Immunol.
Demoly P, Corren J, Creticos P, De Blay F, Gevaert P, Hellings P, Kowal K, Le Gall M, Nenasheva N, Passalacqua G, Pfaar O, Tortajada-Girbés M, Vidal C,
Worm M, Casale TB
doi: 10.1016/j.jaci.