New treatments in respiratory medicine in 2018 : asthma, cystic fibrosis and nocturnal positive pressure (CPAP or NIV)

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AsthmaSleep Apnea

Does Continuous Positive Airway Pressure (CPAP) treatment of obstructive sleep apnoea (OSA) improve asthma-related clinical outcomes in patients with co-existing conditions?- A systematic review

Respir Med.

Davies SE, Bishopp A, Wharton S, Turner AM, Mansur AH

doi: 10.1016/j.rmed.2018.08.004.

Pulmonary Fibrosis

New treatments targeting the basic defects in cystic fibrosis

Presse Med.

Fajac I, Wainwright CE

doi: 10.1016/j.lpm.2017.01.024.

Pulmonary Fibrosis

Respiratory rate in infants with cystic fibrosis throughout the first year of life and association with lung clearance index measured shortly after birth

J Cyst Fibros.

Korten I, Kieninger E, Yammine S, Cangiano G, Nyilas S, Anagnostopoulou P, Singer F, Kuehni CE, Regamey N, Frey U, Casaulta C, Spycher BD, Latzin P; SCILD; BILD study group

doi: 10.1016/j.jcf.2018.07.002.

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Pulmonary Fibrosis

Gaps in the evidence for treatment decisions in cystic fibrosis: a systematic review

Thorax.

Rowbotham NJ, Smith S, Prayle AP, Robinson KA, Smyth AR

doi: 10.1136/thoraxjnl-

AsthmaPulmonary Fibrosis

Pulmonary ventilation imaging in asthma and cystic fibrosis using oxygen-enhanced 3D radial ultrashort echo time MRI

J Magn Reson Imaging.

Zha W, Kruger SJ, Johnson KM, Cadman RV, Bell LC, Liu F, Hahn AD, Evans MD, Nagle SK, Fain SB

doi: 10.1002/jmri.25877.

The use of an alternate side lying positioning strategy during inhalation therapy does not prolong nebulisation time in adults with Cystic Fibrosis: a randomised crossover trial

BMC Pulm Med.

Dentice RL, Elkins MR, Dwyer GM, Bye PTP

doi: 10.1186/s12890-017-0568-2.

Pulmonary Fibrosis

Pharmacokinetics of Continuous Infusion Beta-lactams in the Treatment of Acute Pulmonary Exacerbations in Adult Patients With Cystic Fibrosis

Chest.

Hong LT, Liou TG, Deka R, King JB, Stevens V, Young DC

doi: 10.1016/j.chest.2018.06.002.

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ARDS

Effect of Titrating Positive End-Expiratory Pressure (PEEP) With an Esophageal Pressure-Guided Strategy vs an Empirical High PEEP-Fio2 Strategy on Death and Days Free From Mechanical Ventilation Among Patients With Acute Respiratory Distress Syndrome: A Randomized Clinical Trial

JAMA.

Beitler JR, Sarge T, Banner-Goodspeed VM, Gong MN, Cook D, Novack V, Loring SH, Talmor D, EPVent-2 Study Group

doi: 10.1001/jama.

Asthma

Reconciling Antimicrobial Susceptibility Testing and Clinical Response in Antimicrobial Treatment of Chronic Cystic Fibrosis Lung Infections

Clin Infect Dis.

Waters VJ, Kidd TJ, Canton R, Ekkelenkamp MB, Johansen HK, LiPuma JJ, Bell SC, Elborn JS, Flume PA, VanDevanter DR, Gilligan P, Antimicrobial Resistance International Working Group in Cystic Fibrosis.

doi: 10.1093/cid/ciz364.

Related content

Does Continuous Positive Airway Pressure (CPAP) treatment of obstructive sleep apnoea (OSA) improve asthma-related clinical outcomes in patients with co-existing conditions?- A systematic review

New treatments targeting the basic defects in cystic fibrosis

Respiratory rate in infants with cystic fibrosis throughout the first year of life and association with lung clearance index measured shortly after birth

Gaps in the evidence for treatment decisions in cystic fibrosis: a systematic review

Pulmonary ventilation imaging in asthma and cystic fibrosis using oxygen-enhanced 3D radial ultrashort echo time MRI

The use of an alternate side lying positioning strategy during inhalation therapy does not prolong nebulisation time in adults with Cystic Fibrosis: a randomised crossover trial

Pharmacokinetics of Continuous Infusion Beta-lactams in the Treatment of Acute Pulmonary Exacerbations in Adult Patients With Cystic Fibrosis

Effect of Titrating Positive End-Expiratory Pressure (PEEP) With an Esophageal Pressure-Guided Strategy vs an Empirical High PEEP-Fio2 Strategy on Death and Days Free From Mechanical Ventilation Among Patients With Acute Respiratory Distress Syndrome: A Randomized Clinical Trial

Reconciling Antimicrobial Susceptibility Testing and Clinical Response in Antimicrobial Treatment of Chronic Cystic Fibrosis Lung Infections