Compassionate remdesivir treatment of severe Covid-19 pneumonia in intensive care unit (ICU) and Non-ICU patients: Clinical outcome and differences in post_treatment hospitalisation status

RECOMMENDED

Respiratory Tract Infection

Effect of Remdesivir vs Standard Care on Clinical Status at 11 Days in Patients With Moderate COVID-19: A Randomized Clinical Trial

★ 2 Recommended by Dr Martin Frey, Faculty Member

JAMA.

Spinner CD, Gottlieb RL, Criner GJ, Arribas López JR, Cattelan AM, Soriano Viladomiu A, Ogbuagu O, Malhotra P, Mullane KM, Castagna A, Chai LYA, Roestenberg M, Tsang OTY, Bernasconi E, Le Turnier P, Chang SC, SenGupta D, Hyland RH, Osinusi AO, Cao H, Blair C, Wang H, Gaggar A, Brainard DM, McPhail MJ, Bhagani S, Ahn MY, Sanyal AJ, Huhn G, Marty FM, GS-US-540-5774 Investigators.

doi: 10.1001/jama.2020.16349.

Pneumonia

Effect of Tocilizumab vs Standard Care on Clinical Worsening in Patients Hospitalized With COVID-19 Pneumonia: A Randomized Clinical Trial

JAMA Intern Med.

Salvarani C, Dolci G, Massari M, Merlo DF, Cavuto S, Savoldi L, Bruzzi P, Boni F, Braglia L, Turrà C, Ballerini PF, Sciascia R, Zammarchi L, Para O, Scotton PG, Inojosa WO, Ravagnani V, Salerno ND, Sainaghi PP, Brignone A, Codeluppi M, Teopompi E, Milesi M, Bertomoro P, Claudio N, Salio M, Falcone M, Cenderello G, Donghi L, Del Bono V, Colombelli PL, Angheben A, Passaro A, Secondo G, Pascale R, Piazza I, Facciolongo N, Costantini M, RCT-TCZ-COVID-19 Study Group

doi: 10.1001/jamainternmed.

RECOMMENDED

AsthmaPneumonia

Characteristics and outcomes of asthmatic patients with COVID-19 pneumonia who require hospitalisation

★ 2 Recommended by Dr Martin Frey, Faculty Member

Eur Respir J.

Beurnier A, Jutant EM, Jevnikar M, Boucly A, Pichon J, Preda M, Frank M, Laurent J, Richard C, Monnet X, Duranteau J, Harrois A, Chaumais MC, Bellin MF, Noël N, Bulifon S, Jaïs X, Parent F, Seferian A, Savale L, Sitbon O, Montani D, Humbert M

doi: 10.1183/13993003.01875-2020.

RECOMMENDED

ARDS

Effect of Dexamethasone on Days Alive and Ventilator-Free in Patients With Moderate or Severe Acute Respiratory Distress Syndrome and COVID-19: The CoDEX Randomized Clinical Trial

★ 2 Recommended by Dr Martin Frey, Faculty Member

JAMA.

Tomazini BM, Maia IS, Cavalcanti AB, Berwanger O, Rosa RG, Veiga VC, Avezum A, Lopes RD, Bueno FR, Silva MVAO, Baldassare FP, Costa ELV, Moura RAB, Honorato MO, Costa AN, Damiani LP, Lisboa T, Kawano-Dourado L, Zampieri FG, Olivato GB, Righy C, Amendola CP, Roepke RML, Freitas DHM, Forte DN, Freitas FGR, Fernandes CCF, Melro LMG, Junior GFS, Morais DC, Zung S, Machado FR, Azevedo LCP, COALITION COVID-19 Brazil III Investigators

doi: 10.1001/jama.2020.17021.

RECOMMENDED

Pneumonia

Severe manifestations of SARS-CoV-2 in children and adolescents: from COVID-19 pneumonia to multisystem inflammatory syndrome: a multicentre study in pediatric intensive care units in Spain

★ 2 Recommended by Dr Martin Frey, Faculty Member

Crit Care

García-Salido A, de Carlos Vicente JC, Belda Hofheinz S, Balcells Ramírez J, Slöcker Barrio M, Leóz Gordillo I, Hernández Yuste A, Guitart Pardellans C, Cuervas-Mons Tejedor M, Huidobro Labarga B, Vázquez Martínez JL, Gutiérrez Jimeno M, Oulego-Erróz I, Trastoy Quintela J, Medina Monzón C, Medina Ramos L, Holanda Peña MS, Gil-Antón J, Sorribes Ortí C, Flores González JC, Hernández Palomo RM, Sánchez Ganfornina I, Fernández Romero E, García-Besteiro M, López-Herce Cid J, González Cortés R, Spanish Pediatric Intensive Care Society working group on SARS-CoV-2 infection.

doi: 10.1186/s13054-020-03332-4

RECOMMENDED

ARDS

Nutrition of the COVID-19 patient in the intensive care unit (ICU): a practical guidance

★ 2 Recommended by Dr Martin Frey, Faculty Member

Crit Care.

Thibault R, Seguin P, Tamion F, Pichard C, Singer P

doi: 10.1186/s13054-020-03159-z.

RECOMMENDED

COPDCoughPneumonia

Predicting Clinical Outcome with Phenotypic Clusters in COVID-19 Pneumonia: An Analysis of 12,066 Hospitalized Patients from the Spanish Registry SEMI-COVID-19

★ 1 Recommended by Dr Martin Frey, Faculty Member

★ 1 Recommended by Dr Marcus Hesse, Faculty Member

J Clin Med

Rubio-Rivas M, Corbella X, Mora-Luján JM, Loureiro-Amigo J, López Sampalo A, Yera Bergua C, Esteve Atiénzar PJ, Díez García LF, Gonzalez Ferrer R, Plaza Canteli S, Pérez Piñeiro A, Cortés Rodríguez B, Jorquer Vidal L, Pérez Catalán I, León Téllez M, Martín Oterino JÁ, Martín González MC, Serrano Carrillo de Albornoz JL, García Sardon E, Alcalá Pedrajas JN, Martin-Urda Diez-Canseco A, Esteban Giner MJ, Tellería Gómez P, Ramos-Rincón JM, Gómez-Huelgas R

doi: 10.3390/jcm9113488

RECOMMENDED

ARDSPneumonia

Clinical efficacy of hydroxychloroquine in patients with covid-19 pneumonia who require oxygen: observational comparative study using routine care data

★ 3 Recommended by Dr Martin Frey, Faculty Member

★ 2 Recommended by Dr Marcus Hesse, Faculty Member

BMJ.

Mahévas M, Tran VT, Roumier M, Chabrol A, Paule R, Guillaud C, Fois E, Lepeule R, Szwebel TA, Lescure FX, Schlemmer F, Matignon M, Khellaf M, Crickx E, Terrier B, Morbieu C, Legendre P, Dang J, Schoindre Y, Pawlotsky JM, Michel M, Perrodeau E, Carlier N, Roche N, de Lastours V, Ourghanlian C, Kerneis S, Ménager P, Mouthon L, Audureau E, Ravaud P, Godeau B, Gallien S, Costedoat-Chalumeau N

doi: 10.1136/bmj.m1844.

RECOMMENDED

Pneumonia

Clinical Features and Chest Imaging as Predictors of Intensity of Care in Patients with COVID-19

★ 2 Recommended by Dr Martin Frey, Faculty Member

J Clin Med.

Cocconcelli E, Biondini D, Giraudo C, Lococo S, Bernardinello N, Fichera G, Barbiero G, Castelli G, Cavinato S, Ferrari A, Saetta M, Cattelan A, Spagnolo P, Balestro E

doi: 10.3390/jcm9092990.

Related content

Effect of Remdesivir vs Standard Care on Clinical Status at 11 Days in Patients With Moderate COVID-19: A Randomized Clinical Trial

Effect of Tocilizumab vs Standard Care on Clinical Worsening in Patients Hospitalized With COVID-19 Pneumonia: A Randomized Clinical Trial

Characteristics and outcomes of asthmatic patients with COVID-19 pneumonia who require hospitalisation

Effect of Dexamethasone on Days Alive and Ventilator-Free in Patients With Moderate or Severe Acute Respiratory Distress Syndrome and COVID-19: The CoDEX Randomized Clinical Trial

Severe manifestations of SARS-CoV-2 in children and adolescents: from COVID-19 pneumonia to multisystem inflammatory syndrome: a multicentre study in pediatric intensive care units in Spain

Nutrition of the COVID-19 patient in the intensive care unit (ICU): a practical guidance

Predicting Clinical Outcome with Phenotypic Clusters in COVID-19 Pneumonia: An Analysis of 12,066 Hospitalized Patients from the Spanish Registry SEMI-COVID-19

Clinical efficacy of hydroxychloroquine in patients with covid-19 pneumonia who require oxygen: observational comparative study using routine care data

Clinical Features and Chest Imaging as Predictors of Intensity of Care in Patients with COVID-19