Interpretation of risk loci from genome-wide association studies of Alzheimer's disease

Parkinson’s Disease

Identification of novel risk loci, causal insights, and heritable risk for Parkinson's disease: a meta-analysis of genome-wide association studies

Lancet Neurol.

Nalls MA, Blauwendraat C, Vallerga CL, Heilbron K, Bandres-Ciga S, Chang D, Tan M, Kia DA, Noyce AJ, Xue A, Bras J, Young E, von Coelln R, Simón-Sánchez J, Schulte C, Sharma M, Krohn L, Pihlstrøm L, Siitonen A, Iwaki H, Leonard H, Faghri F, Gibbs JR, Hernandez DG, Scholz SW, Botia JA, Martinez M, Corvol JC, Lesage S, Jankovic J, Shulman LM, Sutherland M, Tienari P, Majamaa K, Toft M, Andreassen OA, Bangale T, Brice A, Yang J, Gan-Or Z, Gasser T, Heutink P, Shulman JM, Wood NW, Hinds DA, Hardy JA, Morris HR, Gratten J, Visscher PM, Graham RR, Singleton AB, 23andMe Research Team., System Genomics of Parkinson's Disease Consortium., International Parkinson's Disease Genomics Consortium.

doi: 10.1016/S1474-4422(19)30320-5.

Impact of home visit capacity on genetic association studies of late-onset Alzheimer's disease

Alzheimers Dement.

Fardo DW, Gibbons LE, Mukherjee S, Glymour MM, McCormick W, McCurry SM, Bowen JD, Larson EB, Crane PK

doi: 10.1016/j.jalz.2017.01.012.

Stroke

Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes

Nat Genet. 2018 Mar 12. doi: 10.1038/s41588-018-0058-3.

doi: 10.1038/s41588-018-0058-3.

Further Publications NeurologyFurther Publications Psychiatry

Genome-wide association study of cerebral small vessel disease reveals established and novel loci

Brain.

Chung J, Marini S, Pera J, Norrving B, Jimenez-Conde J, Roquer J, Fernandez-Cadenas I, Tirschwell DL, Selim M, Brown DL, Silliman SL, Worrall BB, Meschia JF, Demel S, Greenberg SM, Slowik A, Lindgren A, Schmidt R, Traylor M, Sargurupremraj M, Tiedt S, Malik R, Debette S, Dichgans M, Langefeld CD, Woo D, Rosand J, Anderson CD

doi: 10.1093/brain/awz233.

COMMENTED

Multiple Sclerosis

Genome-wide Pleiotropy Between Parkinson Disease and Autoimmune Diseases

Read the related editorial recommended by Dr med. Andreas Hottinger: Parkinson Disease and Autoimmune Disorders-What Can We Learn From Genome-wide Pleiotropy?

doi: 10.1001/

Aging and Cognitive FunctionsAlzheimer’s DiseaseDementia

Associations of the Top 20 Alzheimer Disease Risk Variants With Brain Amyloidosis

JAMA Neurol.

Apostolova LG, Risacher SL, Duran T, Stage EC, Goukasian N, West JD, Do TM, Grotts J, Wilhalme H, Nho K, Phillips M, Elashoff D, Saykin AJ

doi: 10.1001/jamaneurol.

Aging and Cognitive Functions

Identification of genetic variants associated with Huntington's disease progression: a genome-wide association study

Lancet Neurol.

Moss DJH, Pardiñas AF, Langbehn D, Lo K, Leavitt BR, Roos R, Durr A, Mead S; TRACK-HD investigators; REGISTRY investigators, Holmans P, Jones L, Tabrizi SJ

doi: 10.1016/S1474-4422(17)30161-8.

Multiple Sclerosis

Pharmacogenetics of glatiramer acetate therapy for multiple sclerosis: the impact of genome-wide association studies identified disease risk loci

Pharmacogenomics.

Kulakova O, Bashinskaya V, Kiselev I, Baulina N, Tsareva E, Nikolaev R, Kozin M, Shchur S, Favorov A, Boyko A, Favorova O

doi: 10.2217/pgs-2017-0058.

Alzheimer’s DiseaseAnxiety and Depression

Updating the evidence for an association between anxiety and risk of Alzheimer's disease: A meta-analysis of prospective cohort studies

J Affect Disord.

Santabárbara J, Lipnicki DM, Bueno-Notivol J, Olaya-Guzmán B, Villagrasa B, López-Antón R

doi: 10.1016/j.jad.2019.11.065.

Related content