Vitamin C, Hydrocortisone, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Analysis of Real-World Application

Sepsis

Effect of Vitamin C, Hydrocortisone, and Thiamine vs Hydrocortisone Alone on Time Alive and Free of Vasopressor Support Among Patients With Septic Shock: The VITAMINS Randomized Clinical Trial

JAMA.

Fujii T, Luethi N, Young PJ, Frei DR, Eastwood GM, French CJ, Deane AM, Shehabi Y, Hajjar LA, Oliveira G, Udy AA, Orford N, Edney SJ, Hunt AL, Judd HL, Bitker L, Cioccari L, Naorungroj T, Yanase F, Bates S, McGain F, Hudson EP, Al-Bassam W, Dwivedi DB, Peppin C, McCracken P, Orosz J, Bailey M, Bellomo R, VITAMINS Trial Investigators.

doi: 10.1001/jama.2019.22176.

Sepsis

Hydrocortisone Compared with Placebo in Patients with Septic Shock Satisfying the Sepsis-3 Diagnostic Criteria and APROCCHSS Study Inclusion Criteria: A Post Hoc Analysis of the ADRENAL Trial

Anesthesiology.

Venkatesh B, Finfer S, Cohen J, Rajbhandari D, Arabi Y, Bellomo R, Billot L, Glass P, Joyce C, Li Q, McArthur C, Perner A, Rhodes A, Thompson K, Webb S, Myburgh J

doi: 10.1097/ALN.0000000000002955.

Sepsis

Evaluation and Predictors of Fluid Resuscitation in Patients With Severe Sepsis and Septic Shock

Crit Care Med.

Kuttab HI, Lykins JD, Hughes MD, Wroblewski K, Keast EP, Kukoyi O, Kopec JA, Hall S, Ward MA

doi: 10.1097/CCM.0000000000003960.

Sepsis

Early Infectious Disease Consultation Is Associated With Lower Mortality in Patients With Severe Sepsis or Septic Shock Who Complete the 3-Hour Sepsis Treatment Bundle

Open Forum Infect Dis.

Madaline T, Wadskier Montagne F, Eisenberg R, Mowrey W, Kaur J, Malik M, Gendlina I, Guo Y, White D, Pirofski LA, Sarwar U

doi: 10.1093/ofid/ofz408.

Sepsis

Risk of Mortality in Immunocompromised Children With Severe Sepsis and Septic Shock

Crit Care Med.

Lindell RB, Nishisaki A, Weiss SL, Traynor DM, Fitzgerald JC

doi: 10.1097/CCM.0000000000004329.

Sepsis

Blood Purification and Mortality in Sepsis and Septic Shock: A Systematic Review and Meta-analysis of Randomized Trials

Anesthesiology.

Putzu A, Schorer R, Lopez-Delgado JC, Cassina T, Landoni G

doi: 10.1097/ALN.0000000000002820.

Sepsis

Mortality in sepsis and septic shock in Europe, North America and Australia between 2009 and 2019- results from a systematic review and meta-analysis

Crit Care.

Bauer M, Gerlach H, Vogelmann T, Preissing F, Stiefel J, Adam D

doi: 10.1186/s13054-020-02950-2.

Sepsis

Mortality in septic patients treated with vitamin C: a systematic meta-analysis

Crit Care

Scholz SS, Borgstedt R, Ebeling N, Menzel LC, Jansen G, Rehberg S

doi: 10.1186/s13054-020-03438-9

Sepsis

Favorable 90-Day Mortality in Obese Caucasian Patients with Septic Shock According to the Sepsis-3 Definition

J Clin Med.

Mewes C, Böhnke C, Alexander T, Büttner B, Hinz J, Popov AF, Ghadimi M, Beißbarth T, Raddatz D, Meissner K, Quintel M, Bergmann I, Mansur A

doi: 10.3390/jcm9010046.

Related content

Effect of Vitamin C, Hydrocortisone, and Thiamine vs Hydrocortisone Alone on Time Alive and Free of Vasopressor Support Among Patients With Septic Shock: The VITAMINS Randomized Clinical Trial

Hydrocortisone Compared with Placebo in Patients with Septic Shock Satisfying the Sepsis-3 Diagnostic Criteria and APROCCHSS Study Inclusion Criteria: A Post Hoc Analysis of the ADRENAL Trial

Evaluation and Predictors of Fluid Resuscitation in Patients With Severe Sepsis and Septic Shock

Early Infectious Disease Consultation Is Associated With Lower Mortality in Patients With Severe Sepsis or Septic Shock Who Complete the 3-Hour Sepsis Treatment Bundle

Risk of Mortality in Immunocompromised Children With Severe Sepsis and Septic Shock

Blood Purification and Mortality in Sepsis and Septic Shock: A Systematic Review and Meta-analysis of Randomized Trials

Mortality in sepsis and septic shock in Europe, North America and Australia between 2009 and 2019- results from a systematic review and meta-analysis

Mortality in septic patients treated with vitamin C: a systematic meta-analysis

Favorable 90-Day Mortality in Obese Caucasian Patients with Septic Shock According to the Sepsis-3 Definition