Molecular Insights into Human Transmembrane Protease Serine-2 (TMPS2) Inhibitors against SARS-CoV2: Homology Modelling, Molecular Dynamics, and Docking Studies

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Viral Infections, Non-HIV

A Human Pluripotent Stem Cell-based Platform to Study SARS-CoV-2 Tropism and Model Virus Infection in Human Cells and Organoids

Cell Stem Cell.

Yang L, Han Y, Nilsson-Payant BE, Gupta V, Wang P, Duan X, Tang X, Zhu J, Zhao Z, Jaffré F, Zhang T, Kim TW, Harschnitz O, Redmond D, Houghton S, Liu C, Naji A, Ciceri G, Guttikonda S, Bram Y, Nguyen DT, Cioffi M, Chandar V, Hoagland DA, Huang Y, Xiang J, Wang H, Lyden D, Borczuk A, Chen HJ, Studer L, Pan FC, Ho DD, tenOever BR, Evans T, Schwartz RE, Chen S

doi: 10.1016/j.stem.2020.06.015.

Viral Infections, Non-HIV

Identification of potential COVID-19 main protease inhibitors using structure-based pharmacophore approach, molecular docking and repurposing studies

Acta Pharm

Daoud S, Alabed SJ, Dahabiyeh LA

doi: 10.2478/acph-2021-0016

Viral Infections, Non-HIV

Development and validation of a prediction model for severe respiratory failure in hospitalized patients with SARS-Cov-2 infection: a multicenter cohort study (PREDI-CO study)

Clin Microbiol Infect.

Bartoletti M, Giannella M, Scudeller L, Tedeschi S, Rinaldi M, Bussini L, Fornaro G, Pascale R, Pancaldi L, Pasquini Z, Trapani F, Badia L, Campoli C, Tadolini M, Attard L, Puoti M, Merli M, Mussini C, Menozzi M, Meschiari M, Codeluppi M, Barchiesi F, Cristini F, Saracino A, Licci A, Rapuano S, Tonetti T, Gaibani P, Ranieri VM, Viale P, PREDICO study group.

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COMMENTED

ACE2 and TMPRSS2 are expressed on the human ocular surface, suggesting susceptibility to SARS-CoV-2 infection

★ 1 Recommended and commented by Prof. Dr emer. Josef Flammer, Faculty Member

★ 3 Recommended by Prof. Dr Ke Yao, Faculty Member

Ocul Surf.

Zhou L, Xu Z, Castiglione GM, Soiberman US, Eberhart CG, Duh EJ

doi: 10.1016/j.jtos.2020.06.007.

Viral Infections, Non-HIV

Preliminary Identification of Potential Vaccine Targets for the COVID-19 Coronavirus (SARS-CoV-2) Based on SARS-CoV Immunological Studies

Viruses.

Ahmed SF, Quadeer AA, McKay MR

doi: 10.3390/v12030254.

Viral Infections, Non-HIV

Asymptomatic and Human-to-Human Transmission of SARS-CoV-2 in a 2-Family Cluster, Xuzhou, China

Emerg Infect Dis.

Li C, Ji F, Wang L, Wang L, Hao J, Dai M, Liu Y, Pan X, Fu J, Li L, Yang G, Yang J, Yan X, Gu B

doi: 10.3201/eid2607.200718.

Viral Infections, Non-HIV

Role of Low-Molecular-Weight Heparin in Hospitalized Patients With Severe Acute Respiratory Syndrome Coronavirus 2 Pneumonia: A Prospective Observational Study

Open Forum Infect Dis

Falcone M, Tiseo G, Barbieri G, Galfo V, Russo A, Virdis A, Forfori F, Corradi F, Guarracino F, Carrozzi L, Celi A, Santini M, Monzani F, De Marco S, Pistello M, Danesi R, Ghiadoni L, Farcomeni A, Menichetti F, Pisa COVID-19 Study Group .

doi: 10.1093/ofid/ofaa563

Viral Infections, Non-HIV

SARS-CoV-2 productively infects human gut enterocytes

doi: 10.1126/science.abc1669.

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