HIV DNA reservoir and elevated PD-1 expression of CD4&#xA0;T-cell subsets particularly persist in the terminal ileum of HIV-positive patients despite cART

SPECIAL REPORT

HIV / AIDS

11^e Conférence de la Société internationale sur le SIDA (IAS) 2021

SPECIAL REPORT

HIV / AIDS

11. Konferenz der Internationalen AIDS-Gesellschaft (IAS) 2021

HIV / AIDS

HIV-1 persistence following extremely early initiation of antiretroviral therapy (ART) during acute HIV-1 infection: An observational study

PLoS Med.

Henrich TJ, Hatano H, Bacon O, Hogan LE, Rutishauser R, Hill A, Kearney MF, Anderson EM, Buchbinder SP, Cohen SE, Abdel-Mohsen M, Pohlmeyer CW, Fromentin R, Hoh R, Liu AY, McCune JM, Spindler J, Metcalf-Pate K, Hobbs KS, Thanh C, Gibson EA, Kuritzkes DR, Siliciano RF, Price RW, Richman DD, Chomont N, Siliciano JD, Mellors JW, Yukl SA, Blankson JN, Liegler T, Deeks SG

doi: 10.1371/

HIV / AIDS

High levels of genetically-intact HIV in HLA-DR+ memory T-cells indicates their value for reservoir studies

AIDS.

Horsburgh BA, Lee E, Hiener B, Eden JS, Schlub TE, von Stockenstrom S, Odevall L, Milush JM, Liegler T, Sinclair E, Hoh R, Boritz EA, Douek DC, Fromentin R, Chomont N, Deeks SG, Hecht FM, Palmer S

doi: 10.1097/QAD.0000000000002465.

HIV / AIDS

HIV-1 integration sites in CD4+ T-cells during primary, chronic, and late presentation of HIV-1 infection

JCI Insight

Kok YL, Vongrad V, Chaudron SE, Shilaih M, Leemann C, Neumann K, Kusejko K, Di Giallonardo F, Kuster H, Braun DL, Kouyos RD, Günthard HF, Metzner KJ

doi: 10.1172/jci.insight.143940

HIV / AIDS

Early ART-treated perinatally HIV-infected seronegative children demonstrate distinct long-term persistence of HIV-specific T and B cell memory

AIDS.

Cotugno N, Morrocchi E, Rinaldi S, Rocca S, Pepponi I, di Cesare S, Bernardi S, Zangari P, Pallikkuth S, de Armas L, Levy O, Rossi P, Pahwa S, Palma P, EPIICAL Consortium.

doi: 10.1097/QAD.0000000000002485.

HIV / AIDS

HLA class II-Restricted CD8+ T cells in HIV-1 Virus Controllers

Sci Rep.

Nyanhete TE, Frisbee AL, Bradley T, Faison WJ, Robins E, Payne T, Freel SA, Sawant S, Weinhold KJ, Wiehe K, Haynes BF, Ferrari G, Li QJ, Moody MA, Tomaras GD

doi: 10.1038/s41598-

HIV / AIDS

HIV-1 infection and the lack of viral control are associated with greater expression of interleukin-21 receptor on CD8+ T cells

AIDS

Dalel J, Ung SK, Hayes P, Black SL, Joseph S, King DF, Makinde J, Gilmour J, IAVI Protocol C investigators list.

doi: 10.1097/QAD.0000000000002864

HIV / AIDS

Immunophenotypic characterization of TCR γδ T cells and MAIT cells in HIV-infected individuals developing Hodgkin's lymphoma

Infect Agent Cancer

Muller CKS, Spagnuolo J, Audigé A, Chancellor A, Russenberger D, Scherrer AU, Hoffmann M, Kouyos R, Battegay M, De Libero G, Speck RF, Swiss HIV Cohort Study.

doi: 10.1186/s13027-021-00365-4

Infectiology · Anesthesiology · Pain

HIV DNA reservoir and elevated PD-1 expression of CD4 T-cell subsets particularly persist in the terminal ileum of HIV-positive patients despite cART

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11^e Conférence de la Société internationale sur le SIDA (IAS) 2021