Treatment with Rapamycin Can Restore Regulatory T Cell Function in IPEX Patients

T Cells

Counter-regulation of regulatory T cells by autoreactive CD8+ T cells in rheumatoid arthritis

doi: 10.1016/j.jaut.2019.02.001.

T CellsRheumatoid Arthritis

Effect of rituximab treatment on T and B cell subsets in lymph node biopsies of patients with rheumatoid arthritis

Rheumatology (Oxford).

Ramwadhdoebe TH, van Baarsen LGM, Boumans MJH, Bruijnen STG, Safy M, Berger FH, Semmelink JF, van der Laken CJ, Gerlag DM, Thurlings RM, Tak PP

doi: 10.1093/rheumatology/key428.

AcneT Cells

Frequency of circulating subpopulations of T regulatory cells in patients with hidradenitis suppurativa

J Eur Acad Dermatol Venereol.

Hessam S, Gambichler T, Höxtermann S, Skrygan M, Sand M, Garcovich S, Meyer T, Stockfleth E, Bechara FG

doi: 10.1111/jdv.16071.

Allergic DiseasesImmunotherapyT Cells

Der p 1-specific regulatory T cell response during house dust mite allergen immunotherapy

Allergy.

Boonpiyathad T, Sokolowska M, Morita H, Rückert B, Kast JI, Wawrzyniak M, Sangasapaviliya A, Pradubpongsa P, Fuengthong R, Thantiworasit P, Sirivichayakul S, Kwok WW, Ruxrungtham K, Akdis M, Akdis CA

doi: 10.1111/all.13684.

Melanoma and Skin CancerT Cells

T regulatory cells mediate immunosuppresion by adenosine in peripheral blood, sentinel lymph node and TILs from melanoma patients

Cancer Lett.

Di Gennaro P, Gerlini G, Caporale R, Sestini S, Brandani P, Urso C, Pimpinelli N, Borgognoni L

doi: 10.1016/j.canlet.2017.12.032

Further Publications Rheumatology

Novel aspects of regulatory T cell dysfunction as a therapeutic target in giant cell arteritis

Ann Rheum Dis

Adriawan IR, Atschekzei F, Dittrich-Breiholz O, Garantziotis P, Hirsch S, Risser LM, Kosanke M, Schmidt RE, Witte T, Sogkas G

doi: 10.1136/annrheumdis-2021-220955

Selective T-cell depletion targeting CD45RA reduces viremia and enhances early T-cell recovery compared to CD3-targeted T-cell depletion

Transpl Infect Dis.

Triplett BM, Muller B, Kang G, Ying L, Cross SJ, Moen J, Cunningham L, Janssen W, Mamcarz E, Shook DR, Srinivasan A, Choi J, Hayden RT, Leung W

doi: 10.1111/tid.12823.

T Cells

CRISPR screen in regulatory T cells reveals modulators of Foxp3

Nature.

Cortez JT, Montauti E, Shifrut E, Gatchalian J, Zhang Y, Shaked O, Xu Y, Roth TL, Simeonov DR, Zhang Y, Chen S, Li Z, Woo JM, Ho J, Vogel IA, Prator GY, Zhang B, Lee Y, Sun Z, Ifergan I, Van Gool F, Hargreaves DC, Bluestone JA, Marson A, Fang D

doi: 10.1038/s41586-020-2246-4.

ImmunotherapyT Cells

Metabolic support of tumour-infiltrating regulatory T cells by lactic acid

Nature

Watson MJ, Vignali PDA, Mullett SJ, Overacre-Delgoffe AE, Peralta RM, Grebinoski S, Menk AV, Rittenhouse NL, DePeaux K, Whetstone RD, Vignali DAA, Hand TW, Poholek AC, Morrison BM, Rothstein JD, Wendell SG, Delgoffe GM

doi: 10.1038/s41586-020-03045-2

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