Interleukin 1 receptor antagonist (IL1RN) gene variants predict radiographic severity of knee osteoarthritis and risk of incident disease

Osteoarthritis

Association of intermittent and constant knee pain patterns with knee pain severity, radiographic knee osteoarthritis duration and severity

Arthritis Care Res (Hoboken).

Carlesso LC, Hawker GA, Torner J, Lewis CE, Nevitt M, Neogi T, Multicenter Osteoarthritis Study group.

doi: 10.1002/acr.24194.

Osteoarthritis

Development and validation of risk stratification trees for incident slow gait speed in persons at high risk for knee osteoarthritis

Ann Rheum Dis.

Sharma L, Kwoh K, Lee JJ, Cauley J, Jackson R, Hochberg M, Chang AH, Eaton C, Nevitt M, Song J, Almagor O, Chmiel JS

doi: 10.1136/annrheumdis-

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Recreational Physical Activity and Risk of Incident Knee Osteoarthritis: an international meta-analysis of individual participant-level data

Arthritis Rheumatol

Gates LS, Perry TA, Golightly YM, Nelson AE, Callahan LF, Felson D, Nevitt M, Jones G, Cooper C, Batt ME, Sanchez-Santos MT, Arden NK

doi: 10.1002/art.42001

COMMENTED

Spinal Disorders

Ixekizumab, an interleukin-17A antagonist in the treatment of ankylosing spondylitis or radiographic axial spondyloarthritis in patients previously untreated with biological disease-modifying anti-rheumatic drugs (COAST-V): 16 week results of a phase 3 randomised, double-blind, active-controlled and placebo-controlled trial

Lancet.

van der Heijde D, Cheng-Chung Wei J, Dougados M, Mease P, Deodhar A, Maksymowych WP, Van den Bosch F, Sieper J, Tomita T, Landewé R, Zhao F, Krishnan E, Adams DH, Pangallo B, Carlier H; COAST-V study group

doi: 10.1016/S0140-

Osteoarthritis

Clinical and biochemical factors associated with risk of total joint replacement and radiographic progression in osteoarthritis: Data from two phase III clinical trials

Semin Arthritis Rheum.

Bihlet AR, Bjerre-Bastos JJ, Andersen JR, Byrjalsen I, Karsdal MA, Bay-Jensen AC

doi: 10.1016/j.semarthrit.2020.03.002.

Osteoarthritis

Associations between biomarkers of bone and cartilage turnover, gender, pain categories and radiographic severity in knee osteoarthritis

Arthritis Res Ther.

Bihlet AR, Byrjalsen I, Bay-Jensen AC, Andersen JR, Christiansen C, Riis BJ, Karsdal MA

doi: 10.1186/s13075-019-1987-7.

Osteoarthritis

Knee Osteoarthritis after Arthroscopic Partial Meniscectomy: Prevalence and Progression of Radiographic Changes after 5 to 12 Years Compared with Contralateral Knee

J Knee Surg.

Longo UG, Ciuffreda M, Candela V, Rizzello G, D'Andrea V, Mannering N, Berton A, Salvatore G, Denaro V

doi: 10.1055/s-0038-1646926.

Juvenile Idiopathic Arthritis

Treat-to-target using first-line recombinant interleukin-1 receptor antagonist monotherapy in new-onset systemic juvenile idiopathic arthritis: results from a five year follow-up study

Arthritis Rheumatol.

Ter Haar NM, van Dijkhuizen EHP, Swart JF, van Royen-Kerkhof A, El Idrissi A, Leek AP, de Jager W, de Groot MCH, Haitjema S, Holzinger D, Foell D, van Loosdregt J, Wulffraat NM, de Roock S, Vastert SJ

doi: 10.1002/art.40865.

Osteoarthritis

Surgical interventions for symptomatic mild to moderate knee osteoarthritis

Cochrane Database Syst Rev.

Palmer JS, Monk AP, Hopewell S, Bayliss LE, Jackson W, Beard DJ, Price AJ

doi: 10.1002/14651858.

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