Dissecting alterations in human CD8+ T cells with aging by high-dimensional single cell mass cytometry

T Cells

Counter-regulation of regulatory T cells by autoreactive CD8+ T cells in rheumatoid arthritis

doi: 10.1016/j.jaut.2019.02.001.

White matter microstructure alterations correlate with terminally differentiated CD8+ effector T cell depletion in the peripheral blood in mania: Combined DTI and immunological investigation in the different phases of bipolar disorder

Brain Behav Immun.

Magioncalda P, Martino M, Tardito S, Sterlini B, Conio B, Marozzi V, Adavastro G, Capobianco L, Russo D, Parodi A, Kalli F, Nasi G, Altosole T, Piaggio N, Northoff G, Fenoglio D, Inglese M, Filaci G, Amore M

doi: 10.1016/j.bbi.2018.04.017.

Melanoma and Skin CancerImmunotherapy

High-dimensional single-cell analysis predicts response to anti-PD-1 immunotherapy

Nat Med.

Krieg C, Nowicka M, Guglietta S, Schindler S, Hartmann FJ, Weber LM, Dummer R, Robinson MD, Levesque MP, Becher B

doi: 10.1038/nm.4466.

T Cells

A Low Frequency of IL-17-Producing CD8⁺ T-Cells Is Associated With Persistent Immune Activation in People Living With HIV Despite HAART-Induced Viral Suppression

Front Immunol.

Perdomo-Celis F, Feria MG, Taborda NA, Rugeles MT

doi: 10.3389/fimmu.2018.02502.

T Cells

Human CD8⁺ T Cells Exhibit a Shared Antigen Threshold for Different Effector Responses

J Immunol.

Abu-Shah E, Trendel N, Kruger P, Nguyen J, Pettmann J, Kutuzov M, Dushek O

doi: 10.4049/jimmunol.2000525.

T Cells

Quantification of T-Cell and B-Cell Replication History in Aging, Immunodeficiency, and Newborn Screening

Front Immunol.

Verstegen RHJ, Aui PM, Watson E, De Jong S, Bartol SJW, Bosco JJ, Cameron PU, Stirling RG, de Vries E, van Dongen JJM, van Zelm MC

doi: 10.3389/fimmu.2019.02084.

T CellsSystemic Lupus Erythematosus

Hypomethylation of STAT1 and HLA-DRB1 is associated with type-I interferon-dependent HLA-DRB1 expression in lupus CD8+ T cells

Ann Rheum Dis.

Miller S, Tsou PS, Coit P, Gensterblum-Miller E, Renauer P, Rohraff DM, Kilian NC, Schonfeld M, Sawalha AH

doi: 10.1136/annrheumdis-

Selective T-cell depletion targeting CD45RA reduces viremia and enhances early T-cell recovery compared to CD3-targeted T-cell depletion

Transpl Infect Dis.

Triplett BM, Muller B, Kang G, Ying L, Cross SJ, Moen J, Cunningham L, Janssen W, Mamcarz E, Shook DR, Srinivasan A, Choi J, Hayden RT, Leung W

doi: 10.1111/tid.12823.

Further Publications Rheumatology

T cell and antibody responses induced by a single dose of ChAdOx1 nCoV-19 (AZD1222) vaccine in a phase 1/2 clinical trial

Nat Med

Ewer KJ, Barrett JR, Belij-Rammerstorfer S, Sharpe H, Makinson R, Morter R, Flaxman A, Wright D, Bellamy D, Bittaye M, Dold C, Provine NM, Aboagye J, Fowler J, Silk SE, Alderson J, Aley PK, Angus B, Berrie E, Bibi S, Cicconi P, Clutterbuck EA, Chelysheva I, Folegatti PM, Fuskova M, Green CM, Jenkin D, Kerridge S, Lawrie A, Minassian AM, Moore M, Mujadidi Y, Plested E, Poulton I, Ramasamy MN, Robinson H, Song R, Snape MD, Tarrant R, Voysey M, Watson MEE, Douglas AD, Hill AVS, Gilbert SC, Pollard AJ, Lambe T, Oxford COVID Vaccine Trial Group.

doi: 10.1038/s41591-020-01194-5

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Counter-regulation of regulatory T cells by autoreactive CD8+ T cells in rheumatoid arthritis

White matter microstructure alterations correlate with terminally differentiated CD8+ effector T cell depletion in the peripheral blood in mania: Combined DTI and immunological investigation in the different phases of bipolar disorder

High-dimensional single-cell analysis predicts response to anti-PD-1 immunotherapy

A Low Frequency of IL-17-Producing CD8+ T-Cells Is Associated With Persistent Immune Activation in People Living With HIV Despite HAART-Induced Viral Suppression

Human CD8+ T Cells Exhibit a Shared Antigen Threshold for Different Effector Responses

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