A Prevalent CXCR3+ Phenotype of Circulating Follicular Helper T Cells Indicates Humoral Dysregulation in Children with Down Syndrome

Abatacept attenuates T follicular helper-cell-dependent B-cell hyperactivity in primary Sjögren's syndrome

Arthritis Rheumatol.

Verstappen GM, Meiners PM, Corneth OBJ, Visser A, Arends S1, Abdulahad WH, Hendriks RW, Vissink A, Kroese FGM, Bootsma H

doi: 10.1002/art.40165.

Atopic Dermatitis

Treatment for moderate to severe atopic dermatitis in alpine and moderate maritime climates differentially affects helper T cells and memory B cells in children

Clin Exp Allergy.

Heeringa JJ, Fieten KB, Bruins FM, van Hoffen E, Knol EF, Pasmans SGMA, van Zelm MC

doi: 10.1111/cea.13136.

ImmunodeficiencyT Cells

Neutrophil and Granulocytic Myeloid-Derived Suppressor Cell-Mediated T Cell Suppression Significantly Contributes to Immune Dysregulation in Common Variable Immunodeficiency Disorders

J Immunol.

Vlkova M, Chovancova Z, Nechvatalova J, Connelly AN, Davis MD, Slanina P, Travnickova L, Litzman M, Grymova T, Soucek P, Freiberger T, Litzman J, Hel Z

doi: 10.4049/jimmunol.1800102.

T Cells

Reduced PD-1 expression on circulating follicular and conventional FOXP3⁺ Treg cells in children with new onset type 1 diabetes and autoantibody-positive at-risk children

Clin Immunol.

Vecchione A, Gerosa J, Di Fonte R, Jofra T, Pia CM, Napoleone V, Ippolito E, Galvani G, Ragogna F, Stabilini A, Bianconi E, Grogan P, Bonura C, Bonfanti R, Frontino G, Nano R, Melzi R, De Pellegrin M, Laurenzi A, Meschi F, Barera G, Rigamonti A, Indirli R, Bosi E, Piemonti L, Aiuti A, Battaglia M, Fousteri G

doi: 10.1016/j.clim.2019.108319.

ImmunotherapyT Cells

Cytometric analysis of T cell phenotype using cytokine profiling for improved manufacturing of an EBV-specific T cell therapy

Clin Exp Immunol

Cooper RS, Kowalczuk A, Wilkie G, Vickers MA, Turner ML, Campbell JDM, Fraser AR

doi: 10.1111/cei.13640

T Cells

Counter-regulation of regulatory T cells by autoreactive CD8+ T cells in rheumatoid arthritis

doi: 10.1016/j.jaut.2019.02.001.

Selective T-cell depletion targeting CD45RA reduces viremia and enhances early T-cell recovery compared to CD3-targeted T-cell depletion

Transpl Infect Dis.

Triplett BM, Muller B, Kang G, Ying L, Cross SJ, Moen J, Cunningham L, Janssen W, Mamcarz E, Shook DR, Srinivasan A, Choi J, Hayden RT, Leung W

doi: 10.1111/tid.12823.

T Cells

Humoral immune response to adenovirus induce tolerogenic bystander dendritic cells that promote generation of regulatory T cells

PLoS Pathog.

Tran TTP, Eichholz K, Amelio P, Moyer C, Nemerow GR, Perreau M, Mennechet FJD, Kremer EJ

doi: 10.1371/journal.ppat.

Autoimmune Disease

Lymphopenia in primary Sjögren's syndrome is associated with premature aging of naïve CD4+ T cells

Rheumatology (Oxford).

Fessler J, Fasching P, Raicht A, Hammerl S, Weber J, Lackner A, Hermann J, Dejaco C, Graninger WB, Schwinger W, Stradner MH

doi: 10.1093/rheumatology/keaa105.

Related content

Abatacept attenuates T follicular helper-cell-dependent B-cell hyperactivity in primary Sjögren's syndrome

Treatment for moderate to severe atopic dermatitis in alpine and moderate maritime climates differentially affects helper T cells and memory B cells in children

Neutrophil and Granulocytic Myeloid-Derived Suppressor Cell-Mediated T Cell Suppression Significantly Contributes to Immune Dysregulation in Common Variable Immunodeficiency Disorders

Reduced PD-1 expression on circulating follicular and conventional FOXP3+ Treg cells in children with new onset type 1 diabetes and autoantibody-positive at-risk children

Cytometric analysis of T cell phenotype using cytokine profiling for improved manufacturing of an EBV-specific T cell therapy

Counter-regulation of regulatory T cells by autoreactive CD8+ T cells in rheumatoid arthritis

Selective T-cell depletion targeting CD45RA reduces viremia and enhances early T-cell recovery compared to CD3-targeted T-cell depletion

Humoral immune response to adenovirus induce tolerogenic bystander dendritic cells that promote generation of regulatory T cells

Lymphopenia in primary Sjögren's syndrome is associated with premature aging of naïve CD4+ T cells

Reduced PD-1 expression on circulating follicular and conventional FOXP3⁺ Treg cells in children with new onset type 1 diabetes and autoantibody-positive at-risk children