Treatment resistant schizophrenia and neurological soft signs may converge on the same pathology: Evidence from explanatory analysis on clinical, psychopathological, and cognitive variables

Aging and Cognitive FunctionsPsychosis and Schizophrenia

Interplay Among Psychopathologic Variables, Personal Resources, Context-Related Factors, and Real-life Functioning in Individuals With Schizophrenia: A Network Analysis

JAMA Psychiatry.

Galderisi S, Rucci P, Kirkpatrick B, Mucci A, Gibertoni D, Rocca P, Rossi A, Bertolino A, Strauss GP, Aguglia E, Bellomo A, Murri MB, Bucci P, Carpiniello B, Comparelli A, Cuomo A, De Berardis D, Dell'Osso L, Di Fabio F, Gelao B, Marchesi C, Monteleone P, Montemagni C, Orsenigo G19, Pacitti F, Roncone R, Santonastaso P, Siracusano A, Vignapiano A, Vita A, Zeppegno P, Maj M; Italian Network for Research on Psychoses

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Psychosis and Schizophrenia

The critical treatment window of clozapine in treatment-resistant schizophrenia: Secondary analysis of an observational study.

Psychiatry Res.

Yoshimura B, Yada Y, So R, Takaki M, Yamada N

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Psychosis and Schizophrenia

Clozapine as a first- or second-line treatment in schizophrenia: a systematic review and meta-analysis

Acta Psychiatr Scand.

Okhuijsen-Pfeifer C, Huijsman EAH, Hasan A, Sommer IEC, Leucht S, Kahn RS, Luykx JJ

doi: 10.1111/acps.12954.

Further Publications Psychiatry

Clozapine induces metformin-resistant prediabetes/diabetes that is associated with poor clinical efficacy in patients with early treatment-resistant schizophrenia

J Affect Disord

Zhuo C, Xu Y, Wang H, Zhou C, Liu J, Yu X, Shao H, Tian H, Fang T, Li Q, Chen J, Xu S, Ma X, Yang W, Yao C, Li B, Yang A, Chen Y, Huang G, Lin C

doi: 10.1016/j.jad.2021.08.023

Anxiety and Depression

A clinical approach to treatment resistance in depressed patients: What to do when the usual treatments don't work well enough?

World J Biol Psychiatry

Dodd S, Bauer M, Carvalho AF, Eyre H, Fava M, Kasper S, Kennedy SH, Khoo JP, Lopez Jaramillo C, Malhi GS, McIntyre RS, Mitchell PB, Castro AMP, Ratheesh A, Severus E, Suppes T, Trivedi MH, Thase ME, Yatham LN, Young AH, Berk M

doi: 10.1080/15622975.2020.1851052

Aging and Cognitive FunctionsPsychosis and Schizophrenia

Impaired glucose tolerance in first-episode drug-naïve patients with schizophrenia: relationships with clinical phenotypes and cognitive deficits.

Psychol Med.

Chen DC, Du XD, Yin GZ, Yang KB, Nie Y, Wang N, Li YL, Xiu MH, He SC, Yang FD, Cho RY, Kosten TR, Soares JC, Zhao JP, Zhang XY

Bipolar Disorder

The concept and management of acute episodes of treatment-resistant bipolar disorder: a systematic review and exploratory meta-analysis of randomized controlled trials

J Affect Disord.

Fornaro M, Carvalho AF, Fusco A, Anastasia A, Solmi M, Berk M, Sim K, Vieta E, de Bartolomeis A

doi: 10.1016/j.jad.2020.07.109.

Bipolar Disorder

The CINP guidelines on the definition and the evidence-based interventions for treatment-resistant Bipolar disorder

Int J Neuropsychopharmacol.

Fountoulakis KN, Yatham L, Grunze H, Vieta E, Young A, Blier P, Tohen M, Kasper S, Moeller HJ

doi: 10.1093/ijnp/pyz064.

Further Publications NeurologyFurther Publications Psychiatry

WFSBP guidelines on how to grade treatment evidence for clinical guideline development

World J Biol Psychiatry.

Hasan A, Bandelow B, Yatham LN, Berk M, Falkai P, Möller HJ, Kasper S; WFSBP Guideline Task Force Chairs

doi: 10.1080/15622975.

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