A randomized, double-blind study comparing the efficacy and safety of trazodone once-a-day and venlafaxine extended-release for the treatment of patients with major depressive disorder

A randomized, double-blind, placebo-controlled 8-week trial of the efficacy, safety, and tolerability of 5, 10, and 20 mg/day vortioxetine in adults with major depressive disorder

Psychiatry Clin Neurosci.

Nishimura A, Aritomi Y, Sasai K, Kitagawa T, Mahableshwarkar AR

doi: 10.1111/pcn.12565.

Efficacy and safety of adjunctive cariprazine in inadequate responders to antidepressants: a randomized, double-blind, placebo-controlled study in adult patients with major depressive disorder

J Clin Psychiatry.

Durgam S, Earley W, Guo H, Li D, Németh G, Laszlovszky I, Montgomery SA

doi: 10.4088/JCP.15m10070.

Anxiety and DepressionBipolar Disorder

Comparative efficacy and acceptability of 21 antidepressant drugs for the acute treatment of adults with major depressive disorder: a systematic review and network meta-analysis

Lancet.

Cipriani A, Furukawa TA, Salanti G, Chaimani A, Atkinson LZ, Ogawa Y, Leucht S, Ruhe HG, Turner EH, Higgins JPT, Egger M, Takeshima N, Hayasaka Y, Imai H, Shinohara K, Tajika A, Ioannidis JPA, Geddes JR

doi: 10.1016/

Anxiety and Depression

Esketamine Nasal Spray for Rapid Reduction of Depressive Symptoms in Patients with Major Depressive Disorder Who Have Active Suicide Ideation with Intent: Results of a Phase 3, Double-Blind, Randomized Study (ASPIRE II)

Int J Neuropsychopharmacol.

Ionescu DF, Fu DJ, Qiu X, Lane R, Lim P, Kasper S, Hough D, Drevets WC, Manji H, Canuso CM

doi: 10.1093/ijnp/pyaa068.

Migraine and Headache

Erenumab treatment for migraine prevention in Japanese patients: Efficacy and safety results from a Phase 3, randomized, double-blind, placebo-controlled study

Headache

Takeshima T, Sakai F, Hirata K, Imai N, Matsumori Y, Yoshida R, Peng C, Cheng S, Mikol DD

doi: 10.1111/head.14138

Anxiety and Depression

A randomized, double-blind, active placebo-controlled study of efficacy, safety, and durability of repeated vs single subanesthetic ketamine for treatment-resistant depression

Transl Psychiatry.

Shiroma PR, Thuras P, Wels J, Albott CS, Erbes C, Tye S, Lim KO

doi: 10.1038/s41398-020-00897-0.

Further Publications NeurologyFurther Publications Psychiatry

Efficacy and safety of cariprazine in bipolar I depression: A double-blind, placebo-controlled phase 3 study

Bipolar Disord.

Earley W, Burgess MV, Khan B, Rekeda L, Suppes T, Tohen M, Calabrese JR

doi: 10.1111/bdi.12852.

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Cariprazine Treatment of Bipolar Depression: A Randomized Double-Blind Placebo-Controlled Phase 3 Study

Am J Psychiatry.

Earley W, Victoria Burgess M, Rekeda L, Dickinson R, Szatmári B, Németh G, McIntyre RS, Sachs GS, Yatham LN

doi: 10.1176/appi.ajp.

Epilepsy

Efficacy and safety of eslicarbazepine acetate versus controlled-release carbamazepine monotherapy in newly diagnosed epilepsy: A phase III double-blind, randomized, parallel-group, multicenter study

Epilepsia.

Trinka E, Ben-Menachem E, Kowacs PA, Elger C, Keller B, Löffler K, Rocha JF, Soares-da-Silva P

doi: 10.1111/epi.13993.

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