Prognostic Utility of the New Definition of Difficult-to-Treat Resistance Among Patients With Gram-Negative Bloodstream Infections

Drug Resistance

External Validation of Difficult-to-Treat Resistance Prevalence and Mortality Risk in Gram-Negative Bloodstream Infection Using Electronic Health Record Data From 140 US Hospitals

Open Forum Infect Dis.

Kadri SS, Lai YLE, Ricotta EE, Strich JR, Babiker A, Rhee C, Klompas M, Dekker JP, Powers JH 3rd, Danner RL, Adjemian J, NIH Antimicrobial Resistance Outcomes Research Initiative (NIH-ARORI).

doi: 10.1093/ofid/ofz110.

Bacterial Infections

Follow-up blood cultures are associated with improved outcome of patients with gram-negative bloodstream infections: retrospective observational cohort study

Clin Microbiol Infect.

Giannella M, Pascale R, Pancaldi L, Monari C, Ianniruberto S, Malosso P, Bussini L, Bartoletti M, Tedeschi S, Ambretti S, Lewis R, Viale P

doi: 10.1016/j.cmi.2020.01.023.

Drug Resistance

Decontamination Strategies and Bloodstream Infections With Antibiotic-Resistant Microorganisms in Ventilated Patients: A Randomized Clinical Trial

JAMA.

Wittekamp BH, Plantinga NL, Cooper BS, Lopez-Contreras J, Coll P, Mancebo J, Wise MP, Morgan MPG, Depuydt P, Boelens J, Dugernier T, Verbelen V, Jorens PG, Verbrugghe W, Malhotra-Kumar S, Damas P, Meex C, Leleu K, van den Abeele AM, Gomes Pimenta de Matos AF, Fernández Méndez S, Vergara Gomez A, Tomic V, Sifrer F, Villarreal Tello E23, Ruiz Ramos J, Aragao I, Santos C, Sperning RHM, Coppadoro P, Nardi G, Brun-Buisson C, Bonten MJM

doi: 10.1001/jama.2018.13765.

Bacterial Infections

Compositional flux within the intestinal microbiota and risk for bloodstream infection with gram-negative bacteria

Clin Infect Dis.

Stoma I, Littmann ER, Peled JU, Giralt S, van den Brink MRM, Pamer EG, Taur Y

doi: 10.1093/cid/ciaa068.

Colistin alone versus colistin plus meropenem for treatment of severe infections caused by carbapenem-resistant Gram-negative bacteria: an open-label, randomised controlled trial

Lancet Infect Dis.

Paul M, Daikos GL, Durante-Mangoni E, Yahav D, Carmeli Y, Benattar YD, Skiada A, Andini R, Eliakim-Raz N, Nutman A, Zusman O, Antoniadou A, Pafundi PC, Adler A, Dickstein Y, Pavleas I, Zampino R, Daitch V, Bitterman R, Zayyad H, Koppel F, Levi I, Babich T, Friberg LE, Mouton JW, Theuretzbacher U, Leibovici L

doi: 10.1016/

Bacterial InfectionsSepsis

Impact of baseline characteristics on future episodes of bloodstream infections: Multistate model in septic patients with bloodstream infections

Clin Infect Dis.

Vazquez Gusillamet MC, Vazquez R, Noe J, Micek ST, Fraser VJ, Kollef MH

doi: 10.1093/cid/ciz1206.

Drug Resistance

Predictors of multidrug-resistant Pseudomonas aeruginosa in neutropenic patients with bloodstream infection

Clin Microbiol Infect.

Viasus D, Puerta-Alcalde P, Cardozo C, Suárez-Lledó M, Rodríguez-Núñez O, Morata L, Fehér C, Marco F, Chumbita M, Moreno-García E, Fernández-Avilés F, Gutiérrez-Garcia G, Martínez JA, Mensa J, Rovira M, Esteve J, Soriano A, Garcia-Vidal C, Hospital Clínic, Barcelona, Spain.

doi: 10.1016/j.cmi.

Drug Resistance

Chlorhexidine versus routine bathing to prevent multidrug-resistant organisms and all-cause bloodstream infections in general medical and surgical units (ABATE Infection trial): a cluster-randomised trial

Lancet.

Huang SS, Septimus E, Kleinman K, Moody J, Hickok J, Heim L, Gombosev A, Avery TR, Haffenreffer K, Shimelman L, Hayden MK, Weinstein RA, Spencer-Smith C, Kaganov RE, Murphy MV, Forehand T, Lankiewicz J, Coady MH, Portillo L, Sarup-Patel J, Jernigan JA, Perlin JB, Platt R; ABATE Infection trial team

doi: 10.1016/S0140-6736(18)32593-5.

Bacterial Infections

Bacterial pathogens and resistance causing community acquired paediatric bloodstream infections in low- and middle-income countries: a systematic review and meta-analysis

Antimicrob Resist Infect Control.

Droz N, Hsia Y, Ellis S, Dramowski A, Sharland M, Basmaci R

doi: 10.1186/s13756-019-0673-5.

Related content

External Validation of Difficult-to-Treat Resistance Prevalence and Mortality Risk in Gram-Negative Bloodstream Infection Using Electronic Health Record Data From 140 US Hospitals

Follow-up blood cultures are associated with improved outcome of patients with gram-negative bloodstream infections: retrospective observational cohort study

Decontamination Strategies and Bloodstream Infections With Antibiotic-Resistant Microorganisms in Ventilated Patients: A Randomized Clinical Trial

Compositional flux within the intestinal microbiota and risk for bloodstream infection with gram-negative bacteria

Colistin alone versus colistin plus meropenem for treatment of severe infections caused by carbapenem-resistant Gram-negative bacteria: an open-label, randomised controlled trial

Impact of baseline characteristics on future episodes of bloodstream infections: Multistate model in septic patients with bloodstream infections

Predictors of multidrug-resistant Pseudomonas aeruginosa in neutropenic patients with bloodstream infection

Chlorhexidine versus routine bathing to prevent multidrug-resistant organisms and all-cause bloodstream infections in general medical and surgical units (ABATE Infection trial): a cluster-randomised trial

Bacterial pathogens and resistance causing community acquired paediatric bloodstream infections in low- and middle-income countries: a systematic review and meta-analysis