Effect of ivabradine on major adverse cardiovascular events and mortality in critically ill patients: a systematic review and meta-analyses of randomised controlled trials with trial sequential analyses

Back PainChronic Pain

Benefits and harms of spinal manipulative therapy for the treatment of chronic low back pain: systematic review and meta-analysis of randomised controlled trials

BMJ.

Rubinstein SM, de Zoete A, van Middelkoop M, Assendelft WJJ, de Boer MR, van Tulder MW

doi: 10.1136/bmj.l689.

Pain Management

Cupping therapy versus acupuncture for pain-related conditions: a systematic review of randomized controlled trials and trial sequential analysis

Chin Med.

Zhang YJ, Cao HJ, Li XL, Yang XY, Lai BY, Yang GY, Liu JP

doi: 10.1186/s13020-017-0142-0.

Mechanical Ventilation

Effect of a fluid bolus on cardiovascular collapse among critically ill adults undergoing tracheal intubation (PrePARE): a randomised controlled trial

Lancet Respir Med.

Janz DR, Casey JD, Semler MW, Russell DW, Dargin J, Vonderhaar DJ, Dischert KM, West JR, Stempek S, Wozniak J, Caputo N, Heideman BE, Zouk AN, Gulati S, Stigler WS, Bentov I, Joffe AM, Rice TW, PrePARE Investigators., Pragmatic Critical Care Research Group.

doi: 10.1016/S2213-2600(19)30246-2.

COMMENTED

Neuropathic Pain

Sodium-glucose cotransporter protein-2 (SGLT-2) inhibitors and glucagon-like peptide-1 (GLP-1) receptor agonists for type 2 diabetes: systematic review and network meta-analysis of randomised controlled trials

★ 1 Recommended and commented by Prof. emer. Dr Ulrich Keller, Faculty Member

★ 2 Recommended and commented by Prof. Dr emer. Josef Flammer, Faculty Member

BMJ

Palmer SC, Tendal B, Mustafa RA, Vandvik PO, Li S, Hao Q, Tunnicliffe D, Ruospo M, Natale P, Saglimbene V, Nicolucci A, Johnson DW, Tonelli M, Rossi MC, Badve SV, Cho Y, Nadeau-Fredette AC, Burke M, Faruque LI, Lloyd A, Ahmad N, Liu Y, Tiv S, Millard T, Gagliardi L, Kolanu N, Barmanray RD, McMorrow R, Raygoza Cortez AK, White H, Chen X, Zhou X, Liu J, Rodríguez AF, González-Colmenero AD, Wang Y, Li L, Sutanto S, Solis RC, Díaz González-Colmenero F, Rodriguez-Gutierrez R, Walsh M, Guyatt G, Strippoli GFM

doi: 10.1136/bmj.m4573

Chronic Pain

Adverse Effects of Antidepressants for Chronic Pain: A Systematic Review and Meta-analysis

Front Neurol.

Riediger C, Schuster T, Barlinn K, Maier S, Weitz J, Siepmann T

doi: 10.3389/fneur.2017.00307.

Pain ReliefRegional Anesthesia

Functional recovery after knee arthroplasty with regional analgesia: A systematic review and meta-analysis of randomised controlled trials

Eur J Anaesthesiol.

Osinski T, Bekka S, Regnaux JP, Fletcher D, Martinez V

doi: 10.1097/EJA.

Viral Infections, Non-HIV

Effect of Hydrocortisone on 21-Day Mortality or Respiratory Support Among Critically Ill Patients With COVID-19: A Randomized Clinical Trial

JAMA.

Dequin PF, Heming N, Meziani F, Plantefève G, Voiriot G, Badié J, François B, Aubron C, Ricard JD, Ehrmann S, Jouan Y, Guillon A, Leclerc M, Coffre C, Bourgoin H, Lengellé C, Caille-Fénérol C, Tavernier E, Zohar S, Giraudeau B, Annane D, Le Gouge A, CAPE COVID Trial Group and the CRICS-TriGGERSep Network

doi: 10.1001/jama.2020.16761.

Postoperative Pain

Intrathecal Dexmedetomidine and Postoperative Pain: A Systematic Review and Meta-analysis of Randomised Controlled Trials

Eur J Pain.

Paramasivan A, Lopez-Olivio AM, Wai Foong T, Tan YW, Yap APA

doi: 10.1002/ejp.1575.

Respiratory Tract InfectionViral Infections, Non-HIV

Efficacy and Safety of Oseltamivir in Children: Systematic Review and Individual Patient Data Meta-analysis of Randomized Controlled Trials

Clin Infect Dis.

Malosh RE, Martin ET, Heikkinen T, Brooks WA, Whitley RJ, Monto AS

doi: 10.1093/cid/cix1040.

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