Biomarker of extracellular matrix remodelling C1M and proinflammatory cytokine interleukin 6 are related to synovitis and pain in end-stage knee osteoarthritis patients

Back PainChronic Pain

Effect of Opioid vs Nonopioid Medications on Pain-Related Function in Patients With Chronic Back Pain or Hip or Knee Osteoarthritis Pain: The SPACE Randomized Clinical Trial

JAMA.

Krebs EE, Gravely A, Nugent S, Jensen AC, DeRonne B, Goldsmith ES, Kroenke K, Bair MJ, Noorbaloochi S

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Pain Management

Effect of Intra-articular Triamcinolone vs Saline on Knee Cartilage Volume and Pain in Patients With Knee Osteoarthritis: A Randomized Clinical Trial

JAMA.

McAlindon TE, LaValley MP, Harvey WF, Price LL, Driban JB, Zhang M, Ward RJ

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Preoperative Neuropathic Pain Like Symptoms and Central Pain Mechanisms in Knee Osteoarthritis Predicts Poor Outcome 6 Months After Total Knee Replacement Surgery

J Pain.

Kurien T, Arendt-Nielsen L, Petersen KK, Graven-Nielsen T, Scammell BE

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Chronic Pain

Pain, Sensitization, and physical performances in patients with chronic painful knee osteoarthritis or chronic pain following total knee arthroplasty: an explorative study

Eur J Pain.

Larsen JB, Arendt-Nielsen L, Simonsen O, Madeleine P

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Mechanistic pain profiling as a tool to predict the efficacy of 3-week nonsteroidal anti-inflammatory drugs plus paracetamol in patients with painful knee osteoarthritis

Pain.

Petersen KK, Olesen AE, Simonsen O, Arendt-Nielsen L

doi: 10.1097/j.pain.

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Chronic Pain

Inhibition of interleukin-6 function attenuates the central sensitization and pain behavior induced by osteoarthritis

Eur J Pharmacol.

Lin Y, Liu L, Jiang H, Zhou J, Tang Y

doi: 10.1016/j.ejphar.2017.06.032.

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Pain-related functional interference in patients with chronic neuropathic postsurgical pain: an analysis of registry data

Pain.

Stamer UM, Ehrler M, Lehmann T, Meissner W, Fletcher D

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