A Randomized, Double-Blind, Double-Dummy, Placebo-Controlled, Intranasal Human Abuse Potential Study of Oxycodone ARIR, a Novel, Immediate-Release, Abuse-Deterrent Formulation

Pain Relief

Tapentadol prolonged-release for moderate-to-severe chronic osteoarthritis knee pain: a double-blind, randomized, placebo- and oxycodone controlled release-controlled study

Curr Med Res Opin.

Serrie A, Lange B, Steup A

doi: 10.1080/

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Back Pain

Analgesic efficacy, safety, and tolerability of a long-acting abuse-deterrent formulation of oxycodone for moderate-to-severe chronic low back pain in subjects successfully switched from immediate-release oxycodone

doi: 10.2147/JPR.S168836.

Pain Relief

Efficacy and safety of tapentadol prolonged-release for moderate-to-severe chronic osteoarthritis knee pain: a pooled analysis of two double-blind, randomized, placebo- and oxycodone controlled-release studies

Curr Med Res Opin.

Lange B, von Zabern D, Elling C, Dubois C

doi: 10.1080/

Can early oral prolonged-release oxycodone with or without naloxone reduce the duration of epidural analgesia after cystectomy? A 3-arm, randomized, double-blind, placebo-controlled trial

Pain.

Schneider MP, Löffel LM, Furrer MA, Burkhard FC, Kleeb B, Curatolo M, Wuethrich PY

doi: 10.1097/

Bacterial Infections

Hyperimmune bovine colostral anti-CS17 antibodies protect against enterotoxigenic Escherichia coli diarrhea in a randomized, doubled-blind, placebo-controlled human infection model

J Infect Dis.

Savarino SJ, McKenzie R, Tribble DR, Porter CK, O'Dowd A, Sincock SA, Poole ST, DeNearing B, Woods CM, Kim H, Grahek SL, Brinkley C, Crabb JH, Bourgeois AL

doi: 10.1093/infdis/jiz135.

Postoperative Pain

Efficacy and safety of single-dose DFN-15 for treatment of acute postsurgical dental pain: a randomized, double-blind, placebo-controlled study

Pain

Singla N, Bertoch T, Shenoy S, Munjal S

doi: 10.1097/j.pain.0000000000002312

COMMENTED

Chronic Pain

The Pharmacokinetics, Efficacy, and Safety of a Novel Selective-Dose Cannabis Inhaler in Patients with Chronic Pain: A Randomized, Double-Blinded, Placebo-Controlled Trial

★ 3 Recommended and commented by Dr Roland Schreiber, Faculty Member

Eur J Pain.

Almog S, Aharon-Peretz J, Vulfsons S, Ogintz M, Abalia H, Lupo T, Hayon Y, Eisenberg E

doi: 10.1002/ejp.1605.

COMMENTED

Back PainChronic Pain

Opioids for chronic low back pain. An updated systematic review and meta-analysis of efficacy, tolerability and safety in randomized placebo-controlled studies of at least four weeks double-blind duration

★ 3 Recommended and commented by Dr Roland Schreiber, Faculty Member

doi: 10.1002/ejp.1519.

Long-term efficacy and safety of oxycodone-naloxone prolonged-release formulation (up to 180/90 mg daily) - results of the open-label extension phase of a phase III multicenter, multiple-dose, randomized, controlled study