Statin action enriches HDL3 in polyunsaturated phospholipids and plasmalogens and reduces LDL-derived phospholipid hydroperoxides in atherogenic mixed dyslipidemia

Diabetes - GeneralType 2 Diabetes

Alirocumab versus usual lipid-lowering care as add-on to statin therapy in individuals with type 2 diabetes and mixed dyslipidaemia: The ODYSSEY DM-DYSLIPIDEMIA randomized trial

Diabetes Obes Metab.

Ray KK, Leiter LA, Müller-Wieland D, Cariou B, Colhoun HM, Henry RR, Tinahones FJ, Bujas-Bobanovic M, Domenger C, Letierce A, Samuel R, Del Prato S

doi: 10.1111/dom.13257.

Type 2 DiabetesLipids

Liraglutide in combination with metformin may improve the atherogenic lipid profile and decrease C-reactive protein level in statin treated obese patients with coronary artery disease and newly diagnosed type 2 diabetes: A randomized trial

Atherosclerosis.

Anholm C, Kumarathurai P, Pedersen LR, Samkani A, Walzem RL, Nielsen OW, Kristiansen OP, Fenger M, Madsbad S, Sajadieh A, Haugaard SB

doi: 10.1016/j.atherosclerosis.2019.07.007.

RECOMMENDED

Type 2 DiabetesLipids

Alirocumab therapy in individuals with type 2 diabetes mellitus and atherosclerotic cardiovascular disease: analysis of the ODYSSEY DM-DYSLIPIDEMIA and DM-INSULIN studies

★ 3 Recommended by Prof. Dr Isabella Sudano, Faculty Member

Cardiovasc Diabetol.

Ray KK, Del Prato S, Müller-Wieland D, Cariou B, Colhoun HM, Tinahones FJ, Domenger C, Letierce A, Mandel J, Samuel R, Bujas-Bobanovic M, Leiter LA

doi: 10.1186/s12933-019-0951-9.

COMMENTED

Lipids

Baseline and on-statin treatment lipoprotein(a) levels for prediction of cardiovascular events: individual patient-data meta-analysis of statin outcome trials

Lancet.

Willeit P, Ridker PM, Nestel PJ, Simes J, Tonkin AM, Pedersen TR, Schwartz GG, Olsson AG, Colhoun HM, Kronenberg F, Drechsler C, Wanner C, Mora S, Lesogor A, Tsimikas S

doi: 10.1016/S0140-

Management Strategies for Statin-Associated Muscle Symptoms: How Useful Is Same-Statin Rechallenge?

Can J Cardiol.

Brennan ET, Joy TR

doi: 10.1016/j.cjca.2017.02.013.

COMMENTED

Diabetes - GeneralLipids

Prevalence and Predictors of Cholesterol Screening, Awareness, and Statin Treatment Among US Adults With Familial Hypercholesterolemia or Other Forms of Severe Dyslipidemia (1999-2014)

Circulation.

Bucholz EM, Rodday AM, Kolor K, Khoury MJ, de Ferranti SD

doi: 10.1161/CIRCULATIONAHA.

Benefits of Statin Therapy in Patients With Acute Myocardial Infarction With Serum Low-Density Lipoprotein Cholesterol ≤ 50 mg/dl

Am J Cardiol.

Piao ZH, Jin L, Kim JH, Ahn Y, Kim YJ, Cho MC, Kim CJ, Kim HS, Liu B, Jeong MH; Other Korea Acute Myocardial Infarction Registry (KAMIR) Investigators

doi: 10.1016/j.amjcard.

Advances in the management of dyslipidemia

Curr Opin Cardiol.

Kampangkaew J, Pickett S, Nambi V

doi: 10.1097/