Longer-term liraglutide administration at the highest dose approved for obesity increases reward-related orbitofrontal cortex activations to food cues: Implications for plateauing weight loss in response to anti-obesity therapies

Diabetes - GeneralType 2 DiabetesObesity and Bariatric Surgery

Short-term administration of the GLP-1 analog liraglutide decreases circulating leptin and increases GIP levels and these changes are associated with alterations in CNS responses to food cues: A randomized, placebo-controlled, crossover study.

Metabolism.

Farr OM, Tsoukas MA, Triantafyllou G, Dincer F, Filippaios A, Ko BJ, Mantzoros CS

Diabetes - General

Efficacy and safety of semaglutide compared with liraglutide and placebo for weight loss in patients with obesity: a randomised, double-blind, placebo and active controlled, dose-ranging, phase 2 trial

Lancet.

O'Neil PM, Birkenfeld AL, McGowan B, Mosenzon O, Pedersen SD, Wharton S, Carson CG, Jepsen CH, Kabisch M, Wilding JPH

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Obesity and Bariatric Surgery

Short-term effectiveness of low dose liraglutide in combination with metformin versus high dose liraglutide alone in treatment of obese PCOS: randomized trial

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Effects of liraglutide on weight, satiation, and gastric functions in obesity: a randomised, placebo-controlled pilot trial

Lancet Gastroenterol Hepatol.

Halawi H, Khemani D, Eckert D, O'Neill J, Kadouh H, Grothe K, Clark MM, Burton DD, Vella A, Acosta A, Zinsmeister AR, Camilleri M

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Effect of Alternate-Day Fasting on Weight Loss, Weight Maintenance, and Cardioprotection Among Metabolically Healthy Obese Adults: A Randomized Clinical Trial

JAMA Intern Med.

Trepanowski JF, Kroeger CM, Barnosky A, Klempel MC, Bhutani S, Hoddy KK, Gabel K, Freels S, Rigdon J, Rood J, Ravussin E, Varady KA

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Increased Physical Activity Associated with Less Weight Regain Six Years After "The Biggest Loser" Competition

Obesity (Silver Spring).

Kerns JC, Guo J, Fothergill E, Howard L, Knuth ND, Brychta R, Chen KY, Skarulis MC, Walter PJ, Hall KD

doi: 10.1002/oby.21986.

Obesity and Bariatric Surgery

Association of Pharmacological Treatments for Obesity With Weight Loss and Adverse Events: A Systematic Review and Meta-analysis.

JAMA.

Khera R, Murad MH, Chandar AK, Dulai PS, Wang Z, Prokop LJ, Loomba R, Camilleri M, Singh S

doi: 10.1001/jama.2016.7602.

Obesity and Bariatric Surgery

Increase in Physical Activity After Bariatric Surgery Demonstrates Improvement in Weight Loss and Cardiorespiratory Fitness

Obes Surg.

Tettero OM, Aronson T, Wolf RJ, Nuijten MAH, Hopman MTE, Janssen IMC

doi: 10.1007/s11695-018-3439-x.

Obesity and Bariatric Surgery

Early improvement in food cravings are associated with long-term weight loss success in a large clinical sample

Int J Obes (Lond).

Dalton M, Finlayson G, Walsh B, Halseth AE, Duarte C, Blundell JE

doi: 10.1038/ijo.2017.89.

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Short-term administration of the GLP-1 analog liraglutide decreases circulating leptin and increases GIP levels and these changes are associated with alterations in CNS responses to food cues: A randomized, placebo-controlled, crossover study.

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